Immunological biomarkers of tuberculosis
Currently there are no sufficiently validated biomarkers to aid the evaluation of new
tuberculosis vaccine candidates, the improvement of tuberculosis diagnostics or the …
tuberculosis vaccine candidates, the improvement of tuberculosis diagnostics or the …
Procalcitonin assay in systemic inflammation, infection, and sepsis: clinical utility and limitations
KL Becker, R Snider, ES Nylen - Critical care medicine, 2008 - journals.lww.com
Objective: The use of procalcitonin (ProCT) as a marker of several clinical conditions, in
particular, systemic inflammation, infection, and sepsis, will be clarified, and its current …
particular, systemic inflammation, infection, and sepsis, will be clarified, and its current …
Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice
Human infection with Mycobacterium tuberculosis can progress to active disease, be
contained as latent infection, or be eradicated by the host response. Tuberculosis …
contained as latent infection, or be eradicated by the host response. Tuberculosis …
Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs …
Background User-friendly, rapid, inexpensive yet accurate TB diagnostic tools are urgently
needed at points of care in resource-limited settings. We investigated host biomarkers …
needed at points of care in resource-limited settings. We investigated host biomarkers …
Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study
C Yoon, FC Semitala, E Atuhumuza… - The Lancet Infectious …, 2017 - thelancet.com
Background Symptom-based screening for tuberculosis is recommended for all people
living with HIV. This recommendation results in unnecessary Xpert MTB/RIF testing in many …
living with HIV. This recommendation results in unnecessary Xpert MTB/RIF testing in many …
Diagnostic accuracy of C-reactive protein for active pulmonary tuberculosis: a meta-analysis
C Yoon, LH Chaisson, SM Patel, IE Allen… - … of Tuberculosis and …, 2017 - ingentaconnect.com
SETTING: Systematic screening for active pulmonary tuberculosis (PTB) is recommended for
high-risk populations, including people living with the human immunodeficiency virus …
high-risk populations, including people living with the human immunodeficiency virus …
Inflammation and tuberculosis: host‐directed therapies
A Zumla, M Rao, SK Parida… - Journal of Internal …, 2015 - Wiley Online Library
Tuberculosis (TB) is an airborne infectious disease that kills almost two million individuals
every year. Multidrug‐resistant (MDR) TB is caused by strains of Mycobacterium …
every year. Multidrug‐resistant (MDR) TB is caused by strains of Mycobacterium …
[HTML][HTML] Role of C-reactive protein and procalcitonin in differentiation of tuberculosis from bacterial community acquired pneumonia
YA Kang, SY Kwon, HIL Yoon, JH Lee… - The Korean journal of …, 2009 - ncbi.nlm.nih.gov
Methods We conducted a prospective study, enrolling 87 participants with suspected CAP in
a community-based referral hospital. A clinical assessment was performed before treatment …
a community-based referral hospital. A clinical assessment was performed before treatment …
Clinical features and outcomes of COVID-19 admissions in a population with a high prevalence of HIV and tuberculosis: a multicentre cohort study
Background There is still a paucity of evidence on the outcomes of coronavirus disease
2019 (COVID-19) among people living with human immunodeficiency virus (PWH) and …
2019 (COVID-19) among people living with human immunodeficiency virus (PWH) and …
Performance of serum C-reactive protein as a screening test for smear-negative tuberculosis in an ambulatory high HIV prevalence population
D Wilson, M Badri, G Maartens - PLoS One, 2011 - journals.plos.org
Background Delayed diagnosis has contributed to the high mortality of sputum smear-
negative tuberculosis (SNTB) in high HIV prevalence countries. New diagnostic strategies …
negative tuberculosis (SNTB) in high HIV prevalence countries. New diagnostic strategies …