Multi‐omics usually refers to the crossover application of multiple high‐throughput screening
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …

Recent advances in high-throughput technologies have enabled the profiling of multiple
layers of a biological system, including DNA sequence data (genomics), RNA expression …

Abstract WikiPathways (https://www. wikipathways. org) is a biological pathway database
known for its collaborative nature and open science approaches. With the core idea of the …

Molecular knowledge of biological processes is a cornerstone in omics data analysis.
Applied to single‐cell data, such analyses provide mechanistic insights into individual cells …

Over-representation analysis (ORA) is one of the commonest pathway analysis approaches
used for the functional interpretation of metabolomics datasets. Despite the widespread use …

The COVID-19 crisis has elicited a global response by the scientific community that has led
to a burst of publications on the pathophysiology of the virus. However, without coordinated …

Abstract Pathway Data Integration Portal (PathDIP) is an integrated pathway database that
was developed to increase functional gene annotation coverage and reduce bias in …

The elucidation of a compound's Mechanism of Action (MoA) is a challenging task in the
drug discovery process, but it is important in order to rationalise phenotypic findings and to …

Pathway-centric approaches are widely used to interpret and contextualize-omics data.
However, databases contain different representations of the same biological pathway, which …

The cost of drug development continues to rise and may be prohibitive in cases of unmet
clinical need, particularly for rare diseases. Artificial intelligence-based methods are …