Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges

LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

The mechanisms and treatment of asphyxial encephalopathy

G Wassink, ER Gunn, PP Drury, L Bennet… - Frontiers in …, 2014 - frontiersin.org
Acute post-asphyxial encephalopathy occurring around the time of birth remains a major
cause of death and disability. The recent seminal insight that allows active neuroprotective …

[HTML][HTML] Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study

PJ Lally, P Montaldo, V Oliveira, A Soe… - The Lancet …, 2019 - thelancet.com
Background In neonatal encephalopathy, the clinical manifestations of injury can only be
reliably assessed several years after an intervention, complicating early prognostication and …

Neonatal encephalopathy: an inadequate term for hypoxic–ischemic encephalopathy

JJ Volpe - Annals of neurology, 2012 - Wiley Online Library
Abstract This Point of View article addresses neonatal encephalopathy (NE) presumably
caused by hypoxia–ischemia and the terminology currently in wide use for this disorder. The …

The developing nervous system: a series of review articles: neurobiology of hypoxic-ischemic injury in the developing brain

MV Johnston, WH Trescher, A Ishida, W Nakajima… - Pediatric …, 2001 - nature.com
Hypoxic ischemia is a common cause of damage to the fetal and neonatal brain. Although
systemic and cerebrovascular physiologic factors play an important role in the initial phases …

Lasting effects of general anesthetics on the brain in the young and elderly:“mixed picture” of neurotoxicity, neuroprotection and cognitive impairment

L Wu, H Zhao, H Weng, D Ma - Journal of anesthesia, 2019 - Springer
General anesthetics are commonly used in major surgery. To achieve the depth of
anesthesia for surgery, patients are being subjected to a variety of general anesthetics …

Threshold of metabolic acidosis associated with newborn complications

JA Low, BG Lindsay, EJ Derrick - American journal of obstetrics and …, 1997 - Elsevier
OBJECTIVE: Our purpose was to determine the threshold of metabolic acidosis at delivery
associated with newborn complications. STUDY DESIGN: This study was a matched case …

Paralisia cerebral, novas perspectivas terapêuticas

NT Rotta - Jornal de pediatria, 2002 - SciELO Brasil
Objetivo: a revisão da paralisia cerebral tem como objetivo oferecer ao pediatra
informações atualizadas sobre o diagnóstico e tratamento. Fontes dos dados: foram …

Fetal and neonatal origins of altered brain development

S Rees, T Inder - Early human development, 2005 - Elsevier
Abnormal development of the brain during fetal life is now thought to contribute to the
aetiology of many neurological disorders that manifest throughout life. Many factors are …

The biological basis of injury and neuroprotection in the fetal and neonatal brain

S Rees, R Harding, D Walker - International Journal of Developmental …, 2011 - Elsevier
A compromised intrauterine environment that delivers low levels of oxygen and/or nutrients,
or is infected or inflammatory, can result in fetal brain injury, abnormal brain development …