For the past two decades, cellular senescence has been recognized as a central component
of the tumor cell response to chemotherapy and radiation. Traditionally, this form of …

Cellular senescence is a stress response elicited by different molecular insults. Senescence
results in cell cycle exit and is characterised by multiple phenotypic changes such as the …

Cellular senescence, a permanent state of cell cycle arrest accompanied by a complex
phenotype, is an essential mechanism that limits tumorigenesis and tissue damage. In …

Prostate cancer (PCa) is one of the leading causes of cancer-related deaths in men.
Although androgen deprivation therapies (ADT) and antiandrogens confer increased …

Abstract Background Prostate cancer (PCa) is an age-related malignancy in men with a high
incidence rate. PCa treatments face many obstacles due to cancer cell resistance and many …

Background The development of castration-resistant prostate cancer (CRPC) remains a
major obstacle in the treatment of prostate cancer (PCa). Dysregulated mitochondrial …

Cellular senescence is a complex and multistep biological process which cells can undergo
in response to different stresses. Referring to a highly stable cell cycle arrest, cellular …

Cellular senescence is a natural tumor suppression mechanism defined by a stable
proliferation arrest. In the context of cancer treatment, cancer cell therapy-induced …

Loquat (Eriobotrya japonica) is a popular fruit and medicinal plant. Here, a high-quality draft
genome of the E. japonica 'Big Five-pointed Star'cultivar that covers~ 98%(733.32 Mb) of the …

Increasing evidence suggests incomplete recovery of COVID-19 patients, who continue to
suffer from cardiovascular diseases, including cerebral vascular disorders (CVD) and …