The urgent need for new therapies for some devastating neuromuscular diseases (NMDs),
such as Duchenne muscular dystrophy or amyotrophic lateral sclerosis, has led to an …

The X‐linked inherited neuromuscular disorder Duchenne muscular dystrophy is
characterised by primary abnormalities in the membrane cytoskeletal component dystrophin …

Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by absence of the
protein dystrophin, which acts as a structural link between the basal lamina and contractile …

Background Multiple clinical trials to assess the efficacy of AAV-directed gene transfer in
participants with Duchenne muscular dystrophy (DMD) are ongoing. The success of these …

Limb girdle muscular dystrophies (LGMDs) are a group of genetically inherited
neuromuscular diseases with a very variable clinical presentation and overlapping traits …

Background: Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease
caused by mutations in the dystrophin gene. Due to their phenotypic similarity to human …

The absence of dystrophin hypersensitizes skeletal muscle of lower and higher vertebrates
to eccentric contraction (ECC)-induced strength loss. Loss of strength can be accompanied …

Background: Patients with acute respiratory failure (ARF) may need mechanical ventilation
(MV), which can lead to diaphragmatic dysfunction and muscle wasting, thus making difficult …

Many of the almost 1000 different neuromuscular diseases are hereditary, and development
of nextgeneration sequencing has been important for improving diagnosis and …

Sleep of sufficient quality and duration is essential for good health and reduces the risk of
cardiometabolic diseases, cerebrovascular diseases, and dementia. In experimental …