Phagocytosis is a fundamental process of cells to capture and ingest foreign particles. Small
unicellular organisms such as free-living amoeba use this process to acquire food. In …

Bacterial capsules have evolved to be at the forefront of the cell envelope, making them an
essential element of bacterial biology. Efforts to understand the Mycobacterium tuberculosis …

Tuberculosis is a distinctive disease in which the causative agent, Mycobacterium
tuberculosis, can persist in humans for decades by avoiding clearance from host immunity …

Better understanding of the immunological components and their interactions necessary to
prevent or control Mycobacterium tuberculosis (Mtb) infection in humans is critical for …

Mycobacterium tuberculosis (Mtb) can withstand months of antibiotic treatment. An important
goal of tuberculosis research is to shorten the treatment to reduce the burden on patients …

Macrophages play an essential role in the immune system by ingesting and degrading
invading pathogens, initiating an inflammatory response and instructing adaptive immune …

Mycobacterium tuberculosis (Mtb) remains an important human pathogen. The Mtb cell
envelope is a critical bacterial structure that contributes to virulence and pathogenicity …

Abstract Mannose-capped lipoarabinomannan (ManLAM), present in all members of the
Mycobacterium tuberculosis complex and in other pathogenic Mycobacterium spp, is a high …

The biology of mycobacteria is dominated by a complex cell envelope of unique composition
and structure and of exceptionally low permeability. This cell envelope is the basis of many …

Sensitive and specific blood-based assays for the detection of pulmonary and
extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses …