[HTML][HTML] The role of E3 ubiquitin ligases in bone homeostasis and related diseases
The ubiquitin–proteasome system (UPS) dedicates to degrade intracellular proteins to
modulate demic homeostasis and functions of organisms. These enzymatic cascades mark …
modulate demic homeostasis and functions of organisms. These enzymatic cascades mark …
Hedgehog Signalling contributes to trauma-induced tendon heterotopic ossification and regulates osteogenesis through antioxidant pathway in tendon-derived stem …
G Li, Y Deng, K Li, Y Liu, L Wang, Z Wu, C Chen… - Antioxidants, 2022 - mdpi.com
Heterotopic ossification (HO) is defined as the generation of pathological ectopic bony
structures in soft tissues, but the molecular mechanisms of tendon HO are not fully revealed …
structures in soft tissues, but the molecular mechanisms of tendon HO are not fully revealed …
Integral membrane protein 2A is a negative regulator of canonical and non-canonical hedgehog signalling
CC Morales-Alcala, IC Georgiou, AJ Timmis… - Cells, 2021 - mdpi.com
The Hedgehog (Hh) receptor PTCH1 and the integral membrane protein 2A (ITM2A) inhibit
autophagy by reducing autolysosome formation. In this study, we demonstrate that ITM2A …
autophagy by reducing autolysosome formation. In this study, we demonstrate that ITM2A …
Exploring the Role of Extracellular Vesicles in Equine Musculoskeletal Pathologies and Associated Regenerative Therapies
EJ Clarke - 2023 - search.proquest.com
Horses are used in a variety of disciplines, including dressage, show jumping, eventing and
racing. Thus, the equine athlete is predisposed to the development of musculoskeletal …
racing. Thus, the equine athlete is predisposed to the development of musculoskeletal …
The UBR box E3 ligases Poe and Hyd are required for efficient Pericentrin degradation
R Varadarajan, BJ Galletta, CJ Fagerstrom, KP Haase… - bioRxiv, 2022 - biorxiv.org
Centrosomes are the major microtubule organizing centers (MTOC) of many cells and are
composed of centrioles and the pericentriolar material (PCM). Centrosomes are an essential …
composed of centrioles and the pericentriolar material (PCM). Centrosomes are an essential …
[图书][B] Novel mouse models of Col-1 related overlap syndrome, with late onset osteoarthritis
A Blease - 2021 - search.proquest.com
Collagen I is a member of the Collagen superfamily of proteins, the proteins most abundant
in mammals, and an essential component of bones, teeth, skin and connective tissues …
in mammals, and an essential component of bones, teeth, skin and connective tissues …