Colorectal cancer (CRC) is among the most common cancers. In fact, it is placed in the third
place among the most diagnosed cancer in men, after lung and prostate cancer, and in the …

Dominantly acting transforming oncogenes are generally considered to contribute to tumor
development and progression by their direct effects on tumor cell proliferation and …

We report the parametrization of the approximate density functional tight binding method,
DFTB3, for sulfur and phosphorus. The parametrization is done in a framework consistent …

Compiling significant advances from more than a decade of research, this text presents
breakthroughs in the prevention, treatment, and control of cancer-exploring the origin …

Ovarian cancer remains the leading cause of death from gynecologic malignancy in Western
countries. This cancer results from a succession of genetic alterations involving oncogenes …

Skin cancer is one of the most common malignancies affecting humans worldwide, and its
incidence is rapidly increasing. The study of skin carcinogenesis is of major interest for both …

Prenylation of proteins with polyisoprenoids is a functionally important post-translational
modification. Prenylation has been well characterized in mammalian cells1, 2 and has been …

Actin was first identified in non-muscle cells only about three decades ago, and at about the
same time, it was found that actin filaments were disrupted in the malignant transformed …

Senescence is a cellular response preventing tumorigenesis. The Ras oncogene is
frequently activated or mutated in human cancers, but Ras activation is insufficient to …

Oral squamous cell carcinoma (OSCC) of head and neck is associated with high morbidity
and mortality in both Western and Asian countries. Several risk factors for the development …