Portrait of inflammatory response to ionizing radiation treatment

FM Di Maggio, L Minafra, GI Forte, FP Cammarata… - Journal of …, 2015 - Springer
Ionizing radiation (IR) activates both pro-and anti-proliferative signal pathways producing an
imbalance in cell fate decision. IR is able to regulate several genes and factors involved in …

Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology

DR Spitz, EI Azzam, J Jian Li, D Gius - Cancer and Metastasis Reviews, 2004 - Springer
Exposure of eukaryotic cells to ionizing radiation (IR) results in the immediate formation of
free radicals that last a matter of milliseconds. It has been assumed that the subsequent …

Identification of molecular subtypes and a prognostic signature based on inflammation-related genes in colon adenocarcinoma

C Qiu, W Shi, H Wu, S Zou, J Li, D Wang, G Liu… - Frontiers in …, 2021 - frontiersin.org
Both tumour-infiltrating immune cells and inflammation-related genes that can mediate
immune infiltration contribute to the initiation and prognosis of patients with colon cancer. In …

Getting ready for the manned mission to Mars: the astronauts' risk from space radiation

CE Hellweg, C Baumstark-Khan - Naturwissenschaften, 2007 - Springer
Abstract Space programmes are shifting towards planetary exploration and, in particular,
towards missions by human beings to the Moon and to Mars. Radiation is considered to be …

Candidate protein biodosimeters of human exposure to ionizing radiation

F Marchetti, MA Coleman, IM Jones… - International journal of …, 2006 - Taylor & Francis
Purpose: To conduct a literature review of candidate protein biomarkers for individual
radiation biodosimetry of exposure to ionizing radiation. Materials and methods …

BiodosEPR-2006 Meeting: Acute dosimetry consensus committee recommendations on biodosimetry applications in events involving uses of radiation by terrorists …

GA Alexander, HM Swartz, SA Amundson… - Radiation …, 2007 - Elsevier
In the aftermath of a radiological terrorism incident or mass-casualty radiation accident, first
responders and receivers require prior guidance and pre-positioned resources for …

Gene expression profiling after irradiation: clues to understanding acute and persistent responses?

AR Snyder, WF Morgan - Cancer and Metastasis Reviews, 2004 - Springer
Ionizing radiation (IR) is an ever-present hazard to humans primarily due to its mutagenic,
carcinogenic, and cell killing ability. In addition to causing DNA damage, irradiation initiates …

Portrait of transcriptional responses to ultraviolet and ionizing radiation in human cells

KE Rieger, G Chu - Nucleic acids research, 2004 - academic.oup.com
To understand the human response to DNA damage, we used microarrays to measure
transcriptional responses of 10 000 genes to ionizing radiation (IR) and ultraviolet radiation …

Comparison of Explant‐Derived and Enzymatic Digestion‐Derived MSCs and the Growth Factors from Wharton's Jelly

JH Yoon, EY Roh, S Shin, NH Jung… - BioMed research …, 2013 - Wiley Online Library
Wharton's jelly is not only one of the most promising tissue sources for mesenchymal stem
cells (MSCs) but also a source of natural growth factors. To prove that we can get both …

Key mechanisms involved in ionizing radiation-induced systemic effects. A current review

IV Mavragani, DA Laskaratou, B Frey… - Toxicology …, 2016 - academic.oup.com
Organisms respond to physical, chemical and biological threats by a potent inflammatory
response, aimed at preserving tissue integrity and restoring tissue homeostasis and …