Adrenomedullin and tumour microenvironment
IM Larráyoz, S Martínez-Herrero… - Journal of translational …, 2014 - Springer
Adrenomedullin (AM) is a regulatory peptide whose involvement in tumour progression is
becoming more relevant with recent studies. AM is produced and secreted by the tumour …
becoming more relevant with recent studies. AM is produced and secreted by the tumour …
Peptidergic systems and cancer: Focus on tachykinin and calcitonin/calcitonin gene-related peptide families
ML Sánchez, FD Rodríguez, R Coveñas - Cancers, 2023 - mdpi.com
Simple Summary Neurokinins A and B, adrenomedullin, adrenomedullin 2, amylin, and
calcitonin gene-related peptide are essential in different tumors. These peptides are …
calcitonin gene-related peptide are essential in different tumors. These peptides are …
Adrenomedullin contributes to age-related memory loss in mice and is elevated in aging human brains
IM Larrayoz, H Ferrero, E Martisova… - Frontiers in molecular …, 2017 - frontiersin.org
Memory decline is common in elderly individuals and is the hallmark of Alzheimer's disease
(AD). Memory failure follows the loss of synaptic contacts in the cerebral cortex and …
(AD). Memory failure follows the loss of synaptic contacts in the cerebral cortex and …
Lack of adrenomedullin in mouse endothelial cells results in defective angiogenesis, enhanced vascular permeability, less metastasis, and more brain damage
L Ochoa-Callejero, A Pozo-Rodrigálvarez… - Scientific Reports, 2016 - nature.com
Adrenomedullin (AM) is a vasodilating peptide involved in the regulation of circulatory
homeostasis and in the pathophysiology of certain cardiovascular diseases. AM plays …
homeostasis and in the pathophysiology of certain cardiovascular diseases. AM plays …
Adrenomedullin regulates intestinal physiology and pathophysiology
S Martínez-Herrero, A Martínez - Domestic animal endocrinology, 2016 - Elsevier
Adrenomedullin (AM) and proadrenomedullin N-terminal 20 peptide (PAMP) are 2
biologically active peptides produced by the same gene, ADM, with ubiquitous distribution …
biologically active peptides produced by the same gene, ADM, with ubiquitous distribution …
Increased levels of brain adrenomedullin in the neuropathology of Alzheimer's disease
H Ferrero, IM Larrayoz, E Martisova, M Solas… - Molecular …, 2018 - Springer
Alzheimer's disease (AD) is characterized by the loss of synaptic contacts caused in part by
cytoskeleton disruption. Adrenomedullin (AM) is involved in physiological functions such as …
cytoskeleton disruption. Adrenomedullin (AM) is involved in physiological functions such as …
[HTML][HTML] Adrenomedullin as a potential biomarker involved in patients with hereditary hemorrhagic telangiectasia
A Iriarte, L Ochoa-Callejero, J García-Sanmartín… - European journal of …, 2021 - Elsevier
Background Adrenomedullin (AM) is a vasoactive peptide mostly secreted by endothelial
cells with an important role in preserving endothelial integrity. The relationship between AM …
cells with an important role in preserving endothelial integrity. The relationship between AM …
Adrenomedullin protects from experimental autoimmune encephalomyelitis at multiple levels
M Pedreño, M Morell, G Robledo… - Brain, behavior, and …, 2014 - Elsevier
Adrenomedullin is a neuropeptide known for its cardiovascular activities and anti-
inflammatory effects. Here, we investigated the effect of adrenomedullin in a model of …
inflammatory effects. Here, we investigated the effect of adrenomedullin in a model of …
Protein disulphide isomerase can predict the clinical prognostic value and contribute to malignant progression in gliomas
Q Hu, K Huang, C Tao, X Zhu - Journal of Cellular and …, 2020 - Wiley Online Library
Increasing evidence from structural and functional studies has indicated that protein
disulphide isomerase (PDI) has a critical role in the proliferation, survival and metastasis of …
disulphide isomerase (PDI) has a critical role in the proliferation, survival and metastasis of …
Lack of adrenomedullin aggravates acute TNBS-induced colitis symptoms in mice, especially in females
S Martínez-Herrero, IM Larrayoz… - Frontiers in …, 2017 - frontiersin.org
Adrenomedullin (AM) is a biologically active peptide which has been tested as a new
therapy for inflammatory bowel disease (IBD) in animal models and in patients with severe …
therapy for inflammatory bowel disease (IBD) in animal models and in patients with severe …