Osteopontin takes center stage in chronic liver disease
Osteopontin (OPN) was first identified in 1986. The prefix osteo‐means bone; however, OPN
is expressed in other tissues, including liver. The suffix‐pontin means bridge and denotes …
is expressed in other tissues, including liver. The suffix‐pontin means bridge and denotes …
Discovering cell-adhesion peptides in tissue engineering: beyond RGD
As an alternative to natural extracellular matrix (ECM) macromolecules, cell-adhesion
peptides (CAPs) have had tremendous impact on the design of cell culture platforms …
peptides (CAPs) have had tremendous impact on the design of cell culture platforms …
Osteopontin/secreted phosphoprotein‐1 harnesses glial‐, immune‐, and neuronal cell ligand‐receptor interactions to sense and regulate acute and chronic …
A Yim, C Smith, AM Brown - Immunological reviews, 2022 - Wiley Online Library
Osteopontin (OPN) also known by its official gene designation secreted phosphoprotein‐1
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …
Osteopontin in vascular disease: Friend or foe?
ZSY Lok, AN Lyle - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
Inflammatory cytokines are necessary for an acute response to injury and the progressive
healing process. However, when this acute response does not resolve and becomes …
healing process. However, when this acute response does not resolve and becomes …
Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns
DEW Chatterton, DN Nguyen, SB Bering… - The international journal …, 2013 - Elsevier
The human newborn infant is susceptible to gut inflammatory disorders. In particular, growth-
restricted infants or infants born prematurely may develop a severe form of intestinal …
restricted infants or infants born prematurely may develop a severe form of intestinal …
[HTML][HTML] The role of osteopontin in inflammatory processes
SA Lund, CM Giachelli, M Scatena - Journal of cell communication and …, 2009 - Springer
Osteopontin (OPN) is a matricellular protein that mediates diverse biological functions. OPN
is involved in normal physiological processes and is implicated in the pathogenesis of a …
is involved in normal physiological processes and is implicated in the pathogenesis of a …
Current trends in inflammatory and immunomodulatory mediators in sepsis
Review on sepsis mediators, and roles in innate and adaptive immune systems, as well as
implications for therapeutics. Sepsis refers to severe systemic inflammation in response to …
implications for therapeutics. Sepsis refers to severe systemic inflammation in response to …
Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease
M Scatena, L Liaw, CM Giachelli - Arteriosclerosis, thrombosis, and …, 2007 - Am Heart Assoc
Osteopontin (OPN) is a multifunctional molecule highly expressed in chronic inflammatory
and autoimmune diseases, and it is specifically localized in and around inflammatory cells …
and autoimmune diseases, and it is specifically localized in and around inflammatory cells …
Extracellular matrix remodeling in vascular disease: defining its regulators and pathological influence
PK Lin, GE Davis - Arteriosclerosis, Thrombosis, and Vascular …, 2023 - Am Heart Assoc
Because of structural and cellular differences (ie, degrees of matrix abundance and cross-
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …
linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison …
[PDF][PDF] Role of osteopontin in adhesion, migration, cell survival and bone remodeling
Osteopontin (OPN) is a secreted adhesive glycophosphoprotein expressed by several cell
types It is normally produced in bone, teeth, kidney and epithelial lining tissues and is found …
types It is normally produced in bone, teeth, kidney and epithelial lining tissues and is found …