Structural basis for ion selectivity in potassium-selective channelrhodopsins

S Tajima, YS Kim, M Fukuda, YJ Jo, PY Wang… - Cell, 2023 - cell.com
KCR channelrhodopsins (K+-selective light-gated ion channels) have received attention as
potential inhibitory optogenetic tools but more broadly pose a fundamental mystery …

Structural foundations of potassium selectivity in channelrhodopsins

EG Govorunova, OA Sineshchekov, LS Brown… - MBio, 2022 - Am Soc Microbiol
Potassium-selective channelrhodopsins (KCRs) are light-gated K+ channels recently found
in the stramenopile protist Hyphochytrium catenoides. When expressed in neurons, KCRs …

Robust Optogenetic Inhibition with Red-light-sensitive Anion-conducting Channelrhodopsins

J Oppermann, A Rozenberg, T Fabrin… - bioRxiv, 2023 - biorxiv.org
Channelrhodopsins (ChRs) are light-gated ion channels that are widely used to optically
activate or silence electrogenic cells such as neurons. Here, we describe the identification …