The axial spondyloarthritis (axSpA) disease concept has undergone substantial change
from when the entity ankylosing spondylitis was defined by the modified New York criteria in …

Latent class models (LCMs) combine the results of multiple diagnostic tests through a
statistical model to obtain estimates of disease prevalence and diagnostic test accuracy in …

Importance Sepsis is a heterogeneous syndrome. Identification of distinct clinical
phenotypes may allow more precise therapy and improve care. Objective To derive sepsis …

Background Subphenotypes have been identified within heterogeneous diseases such as
asthma and breast cancer, with important therapeutic implications. We assessed whether …

A modern, comprehensive treatment of latent class and latent transition analysis for
categorical data On a daily basis, researchers in the social, behavioral, and health sciences …

Praise for the First Edition"... the book is a valuable addition to the literature in the field,
serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt …

Selecting the number of different classes that will be assumed to exist in the population is an
important step in latent class analysis (LCA). The bootstrap likelihood ratio test (BLRT) …

The second edition features: a CD with all of the book's Amos, EQS, and LISREL programs
and data sets; new chapters on importing data issues related to data editing and on how to …

ContextWhile recent pharmacological advances have generated increased public interest
and demand for clinical services regarding erectile dysfunction, epidemiologic data on …

Background: Many alcohol research questions require methods that take a person‐centered
approach because the interest is in finding heterogeneous groups of individuals, such as …