Thanks to its safety and accessibility, magnetic resonance imaging (MRI) is extensively used
in clinical routine and research field, largely contributing to our understanding of the …

Currently, over five million Americans suffer with Alzheimer's disease (AD). In the absence of
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …

Hippocampal atrophy, as evidenced using magnetic resonance imaging (MRI), is one of the
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …

In this study, we have assessed the validity and reliability of an automated labeling system
that we have developed for subdividing the human cerebral cortex on magnetic resonance …

The NINCDS–ADRDA and the DSM-IV-TR criteria for Alzheimer's disease (AD) are the
prevailing diagnostic standards in research; however, they have now fallen behind the …

Functional magnetic resonance imaging (fMRI) studies have observed hyperactivity in the
hippocampal region in individuals with Mild Cognitive Impairment (MCI). However, the …

Objective: To evaluate the utility of MRI hippocampal and entorhinal cortex atrophy in
predicting conversion from mild cognitive impairment (MCI) to Alzheimer disease (AD) …

Alzheimer's disease (AD) is the most common cause of dementia, affecting the central
nervous system (CNS) through the accumulation of intraneuronal neurofibrillary tau tangles …

Objective: Since Alzheimer disease (AD) neuropathology is thought to develop years before
dementia, it may be possible to detect subtle AD-related atrophy in preclinical AD. Here we …

Background While most patients with mild cognitive impairment (MCI) transition to Alzheimer
disease (AD), others develop non-AD dementia, remain in the MCI state, or improve …