The pharmacological treatment of chronic pain: from guidelines to daily clinical practice

G Marcianò, C Vocca, M Evangelista, C Palleria… - Pharmaceutics, 2023 - mdpi.com
In agreement with the International Association for the Study of Pain, chronic pain is an
unpleasant sensory and emotional experience associated with actual or potential tissue …

Effect of statins on lung cancer molecular pathways: A possible therapeutic role

G Marcianò, C Palleria, A Casarella, V Rania, E Basile… - Pharmaceuticals, 2022 - mdpi.com
Lung cancer is a common neoplasm, usually treated through chemotherapy, radiotherapy
and/or surgery. Both clinical and experimental studies on cancer cells suggest that some …

CYP1A inhibitors: Recent progress, current challenges, and future perspectives

Z Dai, Y Wu, Y Xiong, J Wu, M Wang… - Medicinal Research …, 2024 - Wiley Online Library
Abstract Mammalian cytochrome P450 1A (CYP1A) are key phase I xenobiotic‐metabolizing
enzymes that play a distinctive role in metabolic activation or metabolic clearance of a …

Metalloproteases in Pain Generation and Persistence: A Possible Target?

G Marcianò, C Vocca, V Rania, R Citraro, G De Sarro… - Biomolecules, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are a large family of zinc-dependent proteolytic enzymes
associated with extracellular matrix protein turnover and tissue degradation. They participate …

Residual dizziness after BPPV management: exploring pathophysiology and treatment beyond canalith repositioning maneuvers

ON Özgirgin, H Kingma, L Manzari, M Lacour - Frontiers in Neurology, 2024 - frontiersin.org
Despite the high success rate of canalith repositioning maneuvers (CRMs) in the treatment
of benign paroxysmal positional vertigo (BPPV), a growing number of patients report …

Ibuprofen in the Management of Viral Infections: The Lesson of COVID‐19 for Its Use in a Clinical Setting

G Marcianò, L Muraca, V Rania… - The Journal of Clinical …, 2023 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are commonly used for the management of
fever, pain, and inflammation. However, they have always been considered to have a …

Effectiveness of conservative approaches on otologic signs and symptoms in patients with temporomandibular disorders and Meniere's disease: A systematic review

M Ferrillo, P Viola, A Astorina, G Chiarella, L Fortunato… - CRANIO®, 2024 - Taylor & Francis
Objective This systematic review aimed to evaluate the effectiveness of conservative
approaches on otologic signs and symptoms in patients affected by Menière's Disease (MD) …

The pharmacological treatment of acute vestibular syndrome

P Viola, FM Gioacchini, A Astorina, D Pisani… - Frontiers in …, 2022 - frontiersin.org
Acute vestibular syndrome (AVS) represents a clinical picture that involves urgent
management due to the important procession of symptoms accompanying the event, which …

The Risk of Drug Interactions in Older Primary Care Patients after Hospital Discharge: The Role of Drug Reconciliation

C Vocca, A Siniscalchi, V Rania, C Galati, G Marcianò… - Geriatrics, 2023 - mdpi.com
Introduction: Drug–drug interactions (DDIs) represent an important clinical problem,
particularly in older patients, due to polytherapy, comorbidity, and physiological changes in …

[HTML][HTML] Fexofenadine

KL Craun, MP Schury - 2020 - europepmc.org
Objectives: Identify the mechanism of action of fexofenadine. Describe the adverse effects of
fexofenadine. Review the appropriate monitoring for the toxicity of fexofenadine. Summarize …