[HTML][HTML] Pathological bacterial translocation in liver cirrhosis

R Wiest, M Lawson, M Geuking - Journal of hepatology, 2014 - Elsevier
Humans harbor nearly 100 trillion intestinal bacteria, which in terms of numbers, represents
around ten times more microbial cells than eukaryotic cells. The gastrointestinal (GI) tract …

Integrative physiology of pneumonia

LJ Quinton, AJ Walkey, JP Mizgerd - Physiological reviews, 2018 - journals.physiology.org
Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

Causes and consequences of innate immune dysfunction in cirrhosis

KM Irvine, I Ratnasekera, EE Powell… - Frontiers in …, 2019 - frontiersin.org
Liver cirrhosis is an increasing health burden and public health concern. Regardless of
etiology, patients with cirrhosis are at risk of a range of life-threatening complications …

Immune dysfunction and infections in patients with cirrhosis

AR Bonnel, C Bunchorntavakul, KR Reddy - Clinical gastroenterology and …, 2011 - Elsevier
Patients with cirrhosis are immunocompromised and susceptible to infections. Although
detection and treatment of spontaneous bacterial peritonitis (SBP) have improved, overall …

[PDF][PDF] Bacterial translocation (BT) in cirrhosis

R Wiest, G Garcia‐Tsao - Hepatology, 2005 - Wiley Online Library
Gut flora and bacterial translocation (BT) play an important role in the pathogenesis of the
complications of cirrhosis. Research on the pathogenesis of BT and its clinical significance …

[HTML][HTML] Immune dysfunction in cirrhosis

N Sipeki, P Antal-Szalmas, PL Lakatos… - World journal of …, 2014 - ncbi.nlm.nih.gov
Innate and adaptive immune dysfunction, also referred to as cirrhosis-associated immune
dysfunction syndrome, is a major component of cirrhosis, and plays a pivotal role in the …

Bacterial translocation in the gut

R Wiest, HC Rath - Best Practice & Research Clinical Gastroenterology, 2003 - Elsevier
The human gastrointestinal tract is colonized by a dense population of microorganisms,
referred to as the bacterial flora. Although the gut provides a functional barrier between …

Bacterial infection-related morbidity and mortality in cirrhosis

L Christou, G Pappas, ME Falagas - Official journal of the …, 2007 - journals.lww.com
OBJECTIVES Bacterial infections are acknowledged causes of morbidity and mortality in
cirrhotic patients; yet, apart from spontaneous bacterial peritonitis, other infection issues …

Hyposplenism: a comprehensive review. Part I: basic concepts and causes

BM William, GR Corazza - Hematology, 2007 - Taylor & Francis
Hyposplenism is not a rare condition and can complicate a remarkable number of illnesses.
The two most time-honored diseases associated with the development of hyposplenism are …

Activation of TLR4 induces severe acute pancreatitis-associated spleen injury via ROS-disrupted mitophagy pathway

E Wen, G Xin, W Su, S Li, Y Zhang, Y Dong, X Yang… - Molecular …, 2022 - Elsevier
Severe acute pancreatitis (SAP) is complicated by systemic inflammatory response
syndrome and multiple organ dysfunction, the disease will eventually result in death in …