Role of antibody drug conjugates in the treatment of patients with breast cancer brain metastases
S Pan, JY Gadrey, S Sammons… - Therapeutic …, 2024 - journals.sagepub.com
Breast cancer remains a leading cause of brain metastases (BM), which carry a poor
prognosis. The current approach to managing BMs in breast cancer patients involves a …
prognosis. The current approach to managing BMs in breast cancer patients involves a …
Systemic Therapy in Breast Cancer
C Corti, H Batra-Sharma, M Kelsten… - American Society of …, 2024 - ascopubs.org
Therapeutic advances in breast cancer have significantly improved outcomes in recent
decades. In the early setting, there has been a gradual shift from adjuvant-only to …
decades. In the early setting, there has been a gradual shift from adjuvant-only to …
Impact of concurrent antibody–drug conjugates and radiotherapy on symptomatic radiation necrosis in breast cancer patients with brain metastases: a multicenter …
Y Koide, N Nagai, S Adachi, M Ito, M Kawamura… - Journal of Neuro …, 2024 - Springer
Aim We aimed to investigate the impact of concurrent antibody–drug conjugates (ADC) and
radiotherapy on symptomatic radiation necrosis (SRN) in breast cancer patients with brain …
radiotherapy on symptomatic radiation necrosis (SRN) in breast cancer patients with brain …
[HTML][HTML] Efficacy and safety of antibody-drug conjugates in pretreated HER2-low metastatic breast cancer: A systematic review and network meta-analysis
F Schettini, S Nucera, T Pascual… - Cancer Treatment …, 2024 - Elsevier
Abstract Introduction Antibody-drug conjugates (ADCs) trastuzumab-deruxtecan (T-DXd)
and sacituzumab-govitecan (SG) provided significant progression-free survival (PFS) and …
and sacituzumab-govitecan (SG) provided significant progression-free survival (PFS) and …
Metastatic brain tumors: from development to cutting‐edge treatment
G Tanzhu, L Chen, J Ning, W Xue, C Wang, G Xiao… - MedComm, 2025 - Wiley Online Library
Metastatic brain tumors, also called brain metastasis (BM), represent a challenging
complication of advanced tumors. Tumors that commonly metastasize to the brain include …
complication of advanced tumors. Tumors that commonly metastasize to the brain include …
[HTML][HTML] A pooled analysis of trastuzumab deruxtecan in patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer with brain …
Background This exploratory pooled analysis investigated the efficacy and safety of
trastuzumab deruxtecan (T-DXd) versus comparator treatment in patients with human …
trastuzumab deruxtecan (T-DXd) versus comparator treatment in patients with human …