Neuroimmune mechanisms and therapies mediating post-ischaemic brain injury and repair
T Shichita, H Ooboshi, A Yoshimura - Nature Reviews Neuroscience, 2023 - nature.com
The nervous and immune systems control whole-body homeostasis and respond to various
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …
Impact of mobile stroke units
K Fassbender, F Merzou, M Lesmeister… - Journal of Neurology …, 2021 - jnnp.bmj.com
Since its first introduction in clinical practice in 2008, the concept of mobile stroke unit
enabling prehospital stroke treatment has rapidly expanded worldwide. This review …
enabling prehospital stroke treatment has rapidly expanded worldwide. This review …
Identifying best practices to improve evaluation and management of in-hospital stroke: a scientific statement from the American Heart Association
This scientific statement describes a path to optimizing care for patients who experience an
in-hospital stroke. Although these patients are in a monitored environment, their evaluation …
in-hospital stroke. Although these patients are in a monitored environment, their evaluation …
Progresses and prospects of neuroprotective agents-loaded nanoparticles and biomimetic material in ischemic stroke
J Chen, J Jin, K Li, L Shi, X Wen, F Fang - Frontiers in Cellular …, 2022 - frontiersin.org
Ischemic stroke remains the leading cause of death and disability, while the main
mechanisms of dominant neurological damage in stroke contain excitotoxicity, oxidative …
mechanisms of dominant neurological damage in stroke contain excitotoxicity, oxidative …
Shorter door-to-needle times are associated with better outcomes after intravenous thrombolytic therapy and endovascular thrombectomy for acute ischemic stroke
S Man, N Solomon, B Mac Grory, B Alhanti, K Uchino… - Circulation, 2023 - Am Heart Assoc
Background: Existing data and clinical trials could not determine whether faster intravenous
thrombolytic therapy (IVT) translates into better long-term functional outcomes after acute …
thrombolytic therapy (IVT) translates into better long-term functional outcomes after acute …
Fluorescent Probe for Investigating the Mitochondrial Viscosity and Hydrogen Peroxide Changes in Cerebral Ischemia/Reperfusion Injury
C Fang, Q Deng, K Zhao, Z Zhou, X Zhu, F Liu… - Analytical …, 2024 - ACS Publications
Cerebral ischemia–reperfusion injury (CIRI), a cause of cerebral dysfunction during cerebral
infarction treatment, is closely associated with mitochondrial viscosity and hydrogen …
infarction treatment, is closely associated with mitochondrial viscosity and hydrogen …
An ultrasensitive fluorescent platform for monitoring GSH variation during ischemic stroke
The growing evidence suggests that the disturbance of redox homeostasis in the brain
tissue contributes to the process of tissue damage following ischemic stroke (IS). Tracking …
tissue contributes to the process of tissue damage following ischemic stroke (IS). Tracking …
Phase I trial outcome of amnion cell therapy in patients with ischemic stroke (I-ACT)
Background We proposed a Phase I dose escalation trial to assess the safety of allogeneic
human amniotic epithelial cells (hAECs) in stroke patients with a view to informing the …
human amniotic epithelial cells (hAECs) in stroke patients with a view to informing the …
Bridging thrombolysis in atrial fibrillation stroke is associated with increased hemorrhagic complications without improved outcomes
Background Atrial fibrillation (AF) associated ischemic stroke is associated with worse
functional outcomes, less effective recanalization, and increased rates of hemorrhagic …
functional outcomes, less effective recanalization, and increased rates of hemorrhagic …
Effectiveness and safety of EVT in patients with acute LVO and low NIHSS
Background and purpose There is much uncertainty in endovascular treatment (EVT)
decisions in patients with acute large vessel occlusion (LVO) and mild neurological deficits …
decisions in patients with acute large vessel occlusion (LVO) and mild neurological deficits …