The preservation of cognitive ability by increasing nicotinamide adenine dinucleotide
(NAD+) levels through supplementation with NAD+ precursors has been identified as a …

Alzheimer's disease (AD) is characterized by the progressive degeneration of neuronal
cells. With the increase in aged population, there is a prevalence of irreversible …

Alzheimer's disease (AD) is a highly prevalent neurodegenerative condition that has
devastating effects on individuals, often resulting in dementia. AD is primarily defined by the …

Neurodegeneration is a condition of the central nervous system (CNS) characterized by loss
of neural structures and function. The most common neurodegenerative disorders (NDDs) …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease, affecting more
than 55 million individuals worldwide in 2021. In addition to the “amyloid hypothesis,” an …

Nicotinamide adenine dinucleotide (NAD) is a critical cosubstrate for enzymes involved in
supplying energy to the brain. Nicotinamide riboside (NR), an NAD+ precursor, emerges as …

As the aging population continues to grow rapidly, age-related diseases are becoming an
increasing burden on the healthcare system and a major concern for the well-being of …

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disorder that
primarily affects persons aged 65 years and above. It causes dementia with memory loss …

Introduction: Obesity is associated with impaired learning, but the mechanisms underlying
this cognitive dysfunction are poorly understood. Moreover, whether obesity-induced …

Klotho is recognized as an aging-suppressor protein that is implicated in a variety of
processes and signaling pathways. The anti-inflammatory, anti-apoptotic, anti-oxidant, and …