Assessment of recombinant protein production in E. coli with Time-Gated Surface Enhanced Raman Spectroscopy (TG-SERS)
Abstract Time-Gated Surface-Enhanced Raman spectroscopy (TG-SERS) was utilized to
assess recombinant protein production in Escherichia coli. TG-SERS suppressed the …
assess recombinant protein production in Escherichia coli. TG-SERS suppressed the …
Analysis of Biologics Molecular Descriptors towards Predictive Modelling for Protein Drug Development Using Time-Gated Raman Spectroscopy
J Itkonen, L Ghemtio, D Pellegrino, PJ Jokela… - Pharmaceutics, 2022 - mdpi.com
Pharmaceutical proteins, compared to small molecular weight drugs, are relatively fragile
molecules, thus necessitating monitoring protein unfolding and aggregation during …
molecules, thus necessitating monitoring protein unfolding and aggregation during …
Manufacture of Recombinant Therapeutic Proteins Using Chinese Hamster Ovary Cells in Large‐Scale Bioreactors: History, Methods, and Perspectives
FM Wurm, M de Jesus - Biosimilars of Monoclonal Antibodies: A …, 2016 - Wiley Online Library
In the last three decades, protein yields from recombinant CHO cells in bioreactors have
increased 10‐100 fold, as the result of improvements in media, bioprocess design and cell …
increased 10‐100 fold, as the result of improvements in media, bioprocess design and cell …
Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation
D Richardson, J Itkonen, J Nievas, A Urtti… - SCiEnTiFiC …, 2018 - nature.com
The use of living cells for the synthesis of pharmaceutical proteins, though state-of-the-art, is
hindered by its lengthy process comprising of many steps that may affect the protein's …
hindered by its lengthy process comprising of many steps that may affect the protein's …
Hydrofilná interakčná kvapalinová chromatografia v analýze intaktných glykopeptidov
K Molnárová - 2024 - dspace.cuni.cz
Analýza glykoproteínov predstavuje obrovskú výzvu v rámci glykoproteomiky, a to hlavne
kvôli makro-a mikroheterogenite glykozylácie. Hydrofilná interakčná kvapalinová …
kvôli makro-a mikroheterogenite glykozylácie. Hydrofilná interakčná kvapalinová …
Растительные системы экспрессии в качестве продуцентов рекомбинантных фармацевтически ценных белков
ЕВ Дейнеко, АА Загорская - Вавиловский журнал генетики и …, 2018 - vavilov.elpub.ru
Аннотация Рынок фармацевтически ценных белков–наиболее быстро развивающийся
сегмент экономики. Большая часть биофармацевтиков получена в клетках …
сегмент экономики. Большая часть биофармацевтиков получена в клетках …
Plant expression systems for production of recombinant pharmaceutically important proteins.
EV Deineko, AA Zagorskaya - 2017 - cabidigitallibrary.org
The market of pharmaceutically valuable proteins is the fastest growing segment of the
economy. Most biopharmaceuticals have been obtained in mammalian and microorganism …
economy. Most biopharmaceuticals have been obtained in mammalian and microorganism …