A novel functional neuron group for respiratory rhythm generation in the ventral medulla

H Onimaru, I Homma - Journal of Neuroscience, 2003 - Soc Neuroscience
We visualized respiratory neuron activity covering the entire ventral medulla using optical
recordings in a newborn rat brainstem–spinal cord preparation stained with voltage …

Phox2b, RTN/pFRG neurons and respiratory rhythmogenesis

H Onimaru, K Ikeda, K Kawakami - Respiratory physiology & neurobiology, 2009 - Elsevier
Phox2b-expressing cells in the parafacial region of the ventral medulla are proposed to play
a role in central chemoreception and postnatal survival. Recent findings in the adult rat and …

Current perspectives for the use of gonane progesteronergic drugs in the treatment of central hypoventilation syndromes

C Loiseau, F Cayetanot, F Joubert… - Current …, 2018 - ingentaconnect.com
Background: Central alveolar hypoventilation syndromes (CHS) encompass
neurorespiratory diseases resulting from congenital or acquired neurological disorders …

Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant mice

E Nsegbe, Å Wallén‐Mackenzie… - The Journal of …, 2004 - Wiley Online Library
Nurr1, a transcription factor belonging to the family of nuclear receptors, is expressed at high
levels immediately after birth. Gene‐targeted mice lacking Nurr1 fail to develop midbrain …

Brainstem and hypothalamic areas activated by tissue hypoxia: Fos-like immunoreactivity induced by carbon monoxide inhalation in the rat

L Bodineau, N Larnicol - Neuroscience, 2001 - Elsevier
Acute ambient hypoxia interacts with the ventilatory and cardiocirculatory control systems,
via the concomitant activation of arterial chemoreceptors and tissue oxygen-sensing …

Neuromodulation of the perinatal respiratory network

K Ballanyi - Current neuropharmacology, 2004 - ingentaconnect.com
Breathing movements are initiated and controlled by a neuronal network within the lower
brainstem that is influenced by peripheral and suprapontine inputs. To provide adaptation of …

Different respiratory control systems are affected in homozygous and heterozygous kreisler mutant mice

F Chatonnet, ED Del Toro, O Voiculescu… - European journal of …, 2002 - Wiley Online Library
During embryonic development, restricted expression of the regulatory genes Krox20 and
kreisler are involved in segmentation and antero‐posterior patterning of the hindbrain neural …

Hypoxia‐sensing properties of the newborn rat ventral medullary surface in vitro

N Voituron, A Frugière, J Champagnat… - The Journal of …, 2006 - Wiley Online Library
The ventral medullary surface (VMS) is a region known to exert a respiratory stimulant effect
during hypercapnia. Several studies have suggested its involvement in the central inhibition …

Key brainstem structures activated during hypoxic exposure in one-day-old mice highlight characteristics for modeling breathing network in premature infants

F Joubert, C Loiseau, AS Perrin-Terrin… - Frontiers in …, 2016 - frontiersin.org
We mapped and characterized changes in the activity of brainstem cell groups under
hypoxia in one-day-old newborn mice, an animal model in which the central nervous system …

Characterization of efferent projections of chemosensitive neurons in the caudal parapyramidal area of the rat brain

JL Ribas-Salgueiro, SP Gaytán, J Ribas, R Pásaro - Brain research bulletin, 2005 - Elsevier
The caudal parapyramidal area of the rat brain contains a population of neurons that are
highly sensitive to an increase in the extracellular hydrogen ion concentration ([H+] o). Some …