Whilst initial anatomical studies of frontotemporal dementia focussed on cortical
involvement, the relevance of subcortical structures to the pathophysiology of frontotemporal …

Background Frontotemporal dementia (FTD) phenotypes are classically associated with
distinctive cortical atrophy patterns and regional hypometabolism. However, the spectrum of …

Behavioural variant frontotemporal dementia can present with episodic memory deficits as
severe as those in Alzheimer's disease. Little is known of the integrity of grey matter areas …

Symptoms suggesting altered processing of pain and temperature have been described in
dementia diseases and may contribute importantly to clinical phenotypes, particularly in the …

Subcortical hyperintensities (SH) are a commonly observed phenomenon on MRI of the
aging brain (Kertesz et al., 1988). Conflicting behavioral, cognitive and pathological …

Thalamic atrophy is a common feature across all forms of FTD but little is known about
specific nuclei involvement. We aimed to investigate in vivo atrophy of the thalamic nuclei …

Background Frontotemporal dementia (FTD) is a heterogeneous neurodegenerative
disorder associated with frontal and temporal atrophy. Subcortical involvement has been …

Behavioural variant frontotemporal dementia (bvFTD) and Alzheimer's disease (AD)
dementia are characterised by progressive brain atrophy. Longitudinal MRI volumetry may …

Background The clinical phenotypes of frontotemporal dementia (FTD) are defined by
distinctive clinical features and associated with unique cortical atrophy patterns. Clinical …

Behavioral variant frontotemporal dementia and semantic dementia have been associated
with striatal degeneration, but few studies have delineated striatal subregion volumes in vivo …