DNA methylation is an epigenetic mark that regulates multiple processes, such as gene
expression and genome stability. Mutants and pharmacological treatments have been …

The liverwort Marchantia polymorpha has been utilized as a model for biological studies
since the 18th century. In the past few decades, there has been a Renaissance in its …

RNA-directed DNA methylation (RdDM) is a biological process in which non-coding RNA
molecules direct the addition of DNA methylation to specific DNA sequences. The RdDM …

Epigenetics has been revealed to play a crucial role in the long-term memory in plants.
However, little is known about whether the epigenetic modifications occur with age …

Mammalian brains feature exceptionally high levels of non-CpG DNA methylation alongside
the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role …

Plants have evolved adaptive strategies to cope with pathogen infections that seriously
threaten plant viability and crop productivity. Upon the perception of invading pathogens, the …

Chemical modification of nucleotide bases in DNA provides one mechanism for conveying
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …

During the past few years several high-quality genomes has been published from
Charophyte algae, bryophytes, lycophytes and ferns. These genomes have not only …

Cytosine DNA methylation (5mC) is a widespread base modification in eukaryotic genomes
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …

DNA methylation plays a crucial role in the regulation of plant growth and the biosynthesis of
secondary metabolites. Danshen (Salvia miltiorrhiza) is a valuable Chinese herbal medicine …