Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions

R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue …

P Lips, KD Cashman, C Lamberg-Allardt… - European journal of …, 2019 - academic.oup.com
Vitamin D deficiency (serum 25-hydroxyvitamin D (25 (OH) D)< 50 nmol/L or 20 ng/mL) is
common in Europe and the Middle East. It occurs in< 20% of the population in Northern …

Vitamin D supplementation guidelines

P Pludowski, MF Holick, WB Grant… - The Journal of steroid …, 2018 - Elsevier
Research carried out during the past two-decades extended the understanding of actions of
vitamin D, from regulating calcium and phosphate absorption and bone metabolism to many …

Controversies in vitamin D: a statement from the third international conference

A Giustina, R Bouillon, N Binkley… - Journal of Bone and …, 2020 - academic.oup.com
Abstract The Third International Conference on Controversies in Vitamin D was held in
Gubbio, Italy, September 10–13, 2019. The conference was held as a follow up to previous …

Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium

M Gaksch, R Jorde, G Grimnes, R Joakimsen… - PloS one, 2017 - journals.plos.org
Background Vitamin D deficiency may be a risk factor for mortality but previous meta-
analyses lacked standardization of laboratory methods for 25-hydroxyvitamin D (25 [OH] D) …

Vitamin D and cardiovascular disease prevention

S Pilz, N Verheyen, MR Grübler, A Tomaschitz… - Nature Reviews …, 2016 - nature.com
Vitamin D is a precursor of the steroid hormone calcitriol that is crucial for bone and mineral
metabolism. Both the high prevalence of vitamin D deficiency in the general population and …

Comparing the evidence from observational studies and randomized controlled trials for nonskeletal health effects of vitamin D

WB Grant, BJ Boucher, F Al Anouti, S Pilz - Nutrients, 2022 - mdpi.com
Although observational studies of health outcomes generally suggest beneficial effects with,
or following, higher serum 25-hydroxyvitamin D [25 (OH) D] concentrations, randomized …

[HTML][HTML] Vitamin D and calcium intakes in general pediatric populations: A French expert consensus paper

J Bacchetta, T Edouard, G Laverny, J Bernardor… - Archives de …, 2022 - Elsevier
Objectives Nutritional vitamin D supplements are often used in general pediatrics. Here, the
aim is to address vitamin D supplementation and calcium nutritional intakes in newborns …

The peculiar role of vitamin D in the pathophysiology of cardiovascular and neurodegenerative diseases

M Janjusevic, G Gagno, AL Fluca, L Padoan… - Life sciences, 2022 - Elsevier
Vitamin D is a hormone with both genomic and non-genomic actions. It exerts its activity by
binding vitamin D receptor (VDR), which belongs to the superfamily of nuclear receptors and …

Temporal relationship between vitamin D status and parathyroid hormone in the United States

MH Kroll, C Bi, CC Garber, HW Kaufman, D Liu… - PloS one, 2015 - journals.plos.org
Background Interpretation of parathyroid hormone (iPTH) requires knowledge of vitamin D
status that is influenced by season. Objective Characterize the temporal relationship …