[HTML][HTML] miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
[HTML][HTML] MicroRNAs in stress signaling and human disease
JT Mendell, EN Olson - Cell, 2012 - cell.com
Disease is often the result of an aberrant or inadequate response to physiologic and
pathophysiologic stress. Studies over the last 10 years have uncovered a recurring …
pathophysiologic stress. Studies over the last 10 years have uncovered a recurring …
MicroRNAs in body fluids—the mix of hormones and biomarkers
MA Cortez, C Bueso-Ramos, J Ferdin… - Nature reviews Clinical …, 2011 - nature.com
Since the discovery of microRNAs (miRNAs), the study of these small noncoding RNAs has
steadily increased and more than 10,000 papers have already been published. The great …
steadily increased and more than 10,000 papers have already been published. The great …
MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
AL Kasinski, FJ Slack - Nature Reviews Cancer, 2011 - nature.com
In normal cells multiple microRNAs (miRNAs) converge to maintain a proper balance of
various processes, including proliferation, differentiation and cell death. miRNA …
various processes, including proliferation, differentiation and cell death. miRNA …
Genetic variation in microRNA networks: the implications for cancer research
Many studies have highlighted the role that microRNAs have in physiological processes and
how their deregulation can lead to cancer. More recently, it has been proposed that the …
how their deregulation can lead to cancer. More recently, it has been proposed that the …
[HTML][HTML] Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
MicroRNAs and epigenetics
F Sato, S Tsuchiya, SJ Meltzer, K Shimizu - The FEBS journal, 2011 - Wiley Online Library
MicroRNAs (miRNAs) comprise species of short noncoding RNA that regulate gene
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …
MicroRNA sequence and expression analysis in breast tumors by deep sequencing
TA Farazi, HM Horlings, JJ Ten Hoeve, A Mihailovic… - Cancer research, 2011 - AACR
MicroRNAs (miRNA) regulate many genes critical for tumorigenesis. We profiled miRNAs
from 11 normal breast tissues, 17 noninvasive, 151 invasive breast carcinomas, and 6 cell …
from 11 normal breast tissues, 17 noninvasive, 151 invasive breast carcinomas, and 6 cell …
miRNA dysregulation in breast cancer
L Mulrane, SF McGee, WM Gallagher, DP O'Connor - Cancer research, 2013 - AACR
Abstract miRNAs have emerged, in the last decade, as key players in the carcinogenic
process, with many candidates identified as playing important roles in many aspects of …
process, with many candidates identified as playing important roles in many aspects of …
[HTML][HTML] MicroRNAs involved in carcinogenesis, prognosis, therapeutic resistance, and applications in human triple-negative breast cancer
L Ding, H Gu, X Xiong, H Ao, J Cao, W Lin, M Yu, J Lin… - Cells, 2019 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive, prevalent, and distinct subtype
of breast cancer characterized by high recurrence rates and poor clinical prognosis, devoid …
of breast cancer characterized by high recurrence rates and poor clinical prognosis, devoid …