Background COVID-19 is a respiratory disease caused by a novel coronavirus called as
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Detected for the first …

Host genetic factors significantly influence susceptibility to SARS-CoV-2 infection and
COVID-19 severity. Among these genetic factors are single-nucleotide variants (SNVs) …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19), a pneumonia with extremely heterogeneous clinical …

The hyperinflammatory response caused by SARS-CoV-2 infection contributes to its
severity, and many critically ill patients show features of cytokine storm (CS) syndrome. We …

The contribution of human genes to the variability of disease outcomes has been shown to
be important across infectious diseases. Studies have shown mutations within specific …

Background The relationship between genetic polymorphisms and coronavirus disease
2019 (COVID-19) remains to be inconsistent. This meta-analysis aimed to provide an …

Rare variants affecting host defense against pathogens may be involved in COVID-19
severity, but most rare variants are not expected to have a major impact on the course of …

Abstract Coronavirus disease 2019 (COVID-19) was considered a major public health
burden worldwide. Multiple studies have shown that susceptibility to severe infections and …

3 Discussion Our study did not establish that the expressions of IFNAR2 and TYK2 genes
serve as a predictor of severity of COVID-19, likely due to limitations such as small sample …

Host genetics of COVID-19 patients is constantly evolving and may play an important role in
the management of hospitalized patients and the identification of new biomarkers. In 2022 …