Gingiva-derived mesenchymal stem cells: potential application in tissue engineering and regenerative medicine-a comprehensive review

D Kim, AE Lee, Q Xu, Q Zhang, AD Le - Frontiers in Immunology, 2021 - frontiersin.org
A unique subpopulation of mesenchymal stem cells (MSCs) has been isolated and
characterized from human gingival tissues (GMSCs). Similar to MSCs derived from other …

Role of YAP/TAZ in cell lineage fate determination and related signaling pathways

BC Heng, X Zhang, D Aubel, Y Bai, X Li… - Frontiers in cell and …, 2020 - frontiersin.org
The penultimate effectors of the Hippo signaling pathways YAP and TAZ, are transcriptional
co-activator proteins that play key roles in many diverse biological processes, ranging from …

Exosomes from human gingiva‐derived mesenchymal stem cells combined with biodegradable chitin conduits promote rat sciatic nerve regeneration

F Rao, D Zhang, T Fang, C Lu, B Wang… - Stem cells …, 2019 - Wiley Online Library
At present, repair methods for peripheral nerve injury often fail to get satisfactory result.
Although various strategies have been adopted to investigate the microenvironment after …

3D bio-printed scaffold-free nerve constructs with human gingiva-derived mesenchymal stem cells promote rat facial nerve regeneration

Q Zhang, PD Nguyen, S Shi, JC Burrell, DK Cullen… - Scientific reports, 2018 - nature.com
Despite the promising neuro-regenerative capacities of stem cells, there is currently no
licensed stem cell-based product in the repair and regeneration of peripheral nerve injuries …

Hiding in plain sight: Human gingival fibroblasts as an essential, yet overlooked, tool in regenerative medicine

A Fadl, A Leask - Cells, 2023 - mdpi.com
Adult human gingival fibroblasts (HGFs), the most abundant cells in the oral cavity, are
essential for maintaining oral homeostasis. Compared with other tissues, adult oral mucosal …

Peripheral nerve regeneration with 3D printed bionic scaffolds loading neural crest stem cell derived Schwann cell progenitors

Y Li, S Lv, H Yuan, G Ye, W Mu, Y Fu… - Advanced Functional …, 2021 - Wiley Online Library
Peripheral nerve injuries are one of the most common types of traumatic damage to the
nervous system. Treatment of peripheral nerve injuries aims to promote axon regrowth by …

Stem cells and extracellular vesicles to improve preclinical orofacial soft tissue healing

Z Wang, R Knight, P Stephens… - Stem Cell Research & …, 2023 - Springer
Orofacial soft tissue wounds caused by surgery for congenital defects, trauma, or disease
frequently occur leading to complications affecting patients' quality of life. Scarring and …

The vicious cycle of arterial stiffness and arterial media calcification

G Van den Bergh, B Opdebeeck, PC D'Haese… - Trends in molecular …, 2019 - cell.com
Arterial media calcification and arterial stiffness are independent predictors of
cardiovascular mortality. Both processes reinforce one another, creating a vicious cycle in …

Tissue engineered bands of büngner for accelerated motor and sensory axonal outgrowth

KV Panzer, JC Burrell, KVT Helm, EM Purvis… - … in Bioengineering and …, 2020 - frontiersin.org
Following peripheral nerve injury comprising a segmental defect, the extent of axon
regeneration decreases precipitously with increasing gap length. Schwann cells play a key …

Dental Tissue− derived mesenchymal stem cells: applications in tissue engineering

JR Dave, GB Tomar - Critical Reviews™ in Biomedical …, 2018 - dl.begellhouse.com
In recent years, mesenchymal stem cells (MSCs) derived from dental tissue have gained in
popularity for tissue-engineering and regenerative medicine applications. The highly …