[HTML][HTML] Molecular mechanisms of hepatitis C virus–induced hepatocellular carcinoma

T Vescovo, G Refolo, G Vitagliano, GM Fimia… - Clinical Microbiology …, 2016 - Elsevier
Hepatitis C virus (HCV) is a major leading cause of hepatocellular carcinoma (HCC). HCV-
induced hepatocarcinogenesis is a multistep process resulting from a combination of …

Molecular mechanisms of hepatocarcinogenesis following sustained virological response in patients with chronic hepatitis C virus infection

CN Hayes, P Zhang, Y Zhang, K Chayama - Viruses, 2018 - mdpi.com
Despite the success of direct-acting antiviral (DAA) agents in treating chronic hepatitis C
virus (HCV) infection, the number of cases of HCV-related hepatocellular carcinoma (HCC) …

Antitumor immunostimulatory activity of polysaccharides from Panax japonicus CA Mey: Roles of their effects on CD4+ T cells and tumor associated macrophages

G Shu, S Jiang, J Mu, H Yu, H Duan, X Deng - International Journal of …, 2018 - Elsevier
In this study, chemical properties of polysaccharides from rhizomes of Panax japonicus CA
Mey (PSPJ) were investigated and the antitumor immunostimulatory activity of PSPJ was …

Association between pro-inflammatory diet and liver cancer risk: A Systematic Review and Meta-Analysis

K Chen, F Yang, X Zhu, G Qiao, C Zhang, J Tao… - Public Health …, 2023 - cambridge.org
Objective: This systematic review aimed to investigate the association between dietary
inflammatory potential and liver cancer to provide evidence regarding scientific dietary …

The role of IDO, IL‐10, and TGF‐β in the HCV‐associated chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma

R Yang, N Gao, Q Chang, X Meng… - Journal of Medical …, 2019 - Wiley Online Library
Indoleamine‐2, 3‐dioxygenase (IDO) is an enzyme that catalyzes tryptophan to kynurenine
and studies have revealed that IDO play a vital role in regulation of liver immunity and …

Genetic variants in IL-6 and IL-10 genes and susceptibility to hepatocellular carcinoma in HCV infected patients

I Sghaier, L Mouelhi, NA Rabia, BR Alsaleh… - Cytokine, 2017 - Elsevier
Abstract Background Hepatitis C virus (HCV) infection is the major cause of hepatocellular
carcinoma (HCC), a common primary liver malignancy, and the third leading cause of …

Impact of interleukin IL-6 rs-1474347 and IL-10 rs-1800896 genetic polymorphisms on the susceptibility of HCV-infected Egyptian patients to hepatocellular carcinoma

RM Abd El-Baky, HF Hetta, G Koneru, M Ammar… - Immunologic …, 2020 - Springer
Hepatitis C virus (HCV) is considered leading cause of cirrhosis and hepatocellular
carcinoma (HCC). We aimed to examine the association of IL-6 and IL-10 single-nucleotide …

Association of IL-10–592 C> A/-1082 A> G and the TNFα-308 G> A with susceptibility to COVID-19 and clinical outcomes

RE Eldesouki, RM Kishk, NM Abd El-Fadeal… - BMC medical …, 2024 - Springer
Background Variation in host immune responses to SARS-CoV-2 is regulated by multiple
genes involved in innate viral response and cytokine storm emergence like IL-10 and TNFa …

Association between IL-10 gene polymorphisms (− 1082 A/G,-819 T/C,-592 A/C) and hepatocellular carcinoma: a meta-analysis and trial sequential analysis

TTY Mei, HH Aung, WS Tung, C Naing - BMC cancer, 2023 - Springer
Background The carcinogenesis of hepatocellular carcinoma is complicated, and genetic
factor may have the role in the malignant transformation of liver cells. IL-10 gene …

Association of IL6 and IL10 gene promotor polymorphisms with susceptibility to acute necrotizing encephalopathy

A Hoshino, N Takahashi, A Oka… - Frontiers in …, 2023 - frontiersin.org
Objective Acute necrotizing encephalopathy (ANE) is a severe complication of infectious
diseases affecting the brain and systemic organs. The main pathogenesis is cytokine storm …