Karyopherin-mediated nucleocytoplasmic transport
Efficient and regulated nucleocytoplasmic trafficking of macromolecules to the correct
subcellular compartment is critical for proper functions of the eukaryotic cell. The majority of …
subcellular compartment is critical for proper functions of the eukaryotic cell. The majority of …
Ivermectin for preventing and treating COVID‐19
M Popp, M Stegemann, MI Metzendorf… - Cochrane Database …, 2021 - cochranelibrary.com
Background Ivermectin, an antiparasitic agent used to treat parasitic infestations, inhibits the
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …
[HTML][HTML] Effect of ivermectin on time to resolution of symptoms among adults with mild COVID-19: a randomized clinical trial
E López-Medina, P López, IC Hurtado, DM Dávalos… - Jama, 2021 - jamanetwork.com
Importance Ivermectin is widely prescribed as a potential treatment for COVID-19 despite
uncertainty about its clinical benefit. Objective To determine whether ivermectin is an …
uncertainty about its clinical benefit. Objective To determine whether ivermectin is an …
An update on current therapeutic drugs treating COVID-19
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented …
COVID-19: a multidisciplinary review
N Chams, S Chams, R Badran, A Shams… - Frontiers in public …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that
is responsible for the 2019–2020 pandemic. In this comprehensive review, we discuss the …
is responsible for the 2019–2020 pandemic. In this comprehensive review, we discuss the …
A review of SARS-CoV-2 and the ongoing clinical trials
YF Tu, CS Chien, AA Yarmishyn, YY Lin… - International journal of …, 2020 - mdpi.com
The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in
Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a …
Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a …
[HTML][HTML] Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen
F Heidary, R Gharebaghi - The Journal of antibiotics, 2020 - nature.com
Ivermectin proposes many potentials effects to treat a range of diseases, with its
antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective …
antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective …
[HTML][HTML] Natural history of COVID-19 and current knowledge on treatment therapeutic options
WG Dos Santos - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Despite intense research there is currently no effective vaccine available against the new
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the later 2019 …
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the later 2019 …
[HTML][HTML] The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
Although several clinical trials are now underway to test possible therapies, the worldwide
response to the COVID-19 outbreak has been largely limited to monitoring/containment. We …
response to the COVID-19 outbreak has been largely limited to monitoring/containment. We …
[HTML][HTML] Review of the emerging evidence demonstrating the efficacy of ivermectin in the prophylaxis and treatment of COVID-19
Background: After COVID-19 emerged on US shores, providers began reviewing the
emerging basic science, translational, and clinical data to identify potentially effective …
emerging basic science, translational, and clinical data to identify potentially effective …