The mechanical role of the cervix in pregnancy

KM Myers, H Feltovich, E Mazza, J Vink, M Bajka… - Journal of …, 2015 - Elsevier
Appropriate mechanical function of the uterine cervix is critical for maintaining a pregnancy
to term so that the fetus can develop fully. At the end of pregnancy, however, the cervix must …

Biomechanics of the human uterus

KM Myers, D Elad - Wiley Interdisciplinary Reviews: Systems …, 2017 - Wiley Online Library
The appropriate biomechanical function of the uterus is required for the execution of human
reproduction. These functions range from aiding the transport of the embryo to the …

Dynamic in vitro culture of bovine and human ovarian tissue enhances follicle progression and health

V Barbato, V Genovese, V De Gregorio, M Di Nardo… - Scientific Reports, 2023 - nature.com
In vitro ovarian cortical tissue culture, followed by culture of isolated secondary follicles, is a
promising future option for production of mature oocytes. Although efforts have been made …

Investigating the mechanical function of the cervix during pregnancy using finite element models derived from high-resolution 3D MRI

M Fernandez, M House, S Jambawalikar… - Computer methods in …, 2016 - Taylor & Francis
Preterm birth is a strong contributor to perinatal mortality, and preterm infants that survive are
at risk for long-term morbidities. During most of pregnancy, appropriate mechanical function …

Three-dimensional anisotropic hyperelastic constitutive model describing the mechanical response of human and mouse cervix

L Shi, L Hu, N Lee, S Fang, K Myers - Acta Biomaterialia, 2022 - Elsevier
The mechanical function of the uterine cervix is critical for a healthy pregnancy. During
pregnancy, the cervix undergoes significant softening to allow for a successful delivery …

A continuous fiber distribution material model for human cervical tissue

KM Myers, CP Hendon, Y Gan, W Yao, K Yoshida… - Journal of …, 2015 - Elsevier
The uterine cervix during pregnancy is the vital mechanical barrier which resists
compressive and tensile loads generated from a growing fetus. Premature cervical …

Adaptable test bench for ASTM-compliant permeability measurement of porous scaffolds for tissue engineering

S Gabetti, B Masante, A Schiavi, E Scatena… - Scientific Reports, 2024 - nature.com
Intrinsic permeability describes the ability of a porous medium to be penetrated by a fluid.
Considering porous scaffolds for tissue engineering (TE) applications, this macroscopic …

Measuring the compressive viscoelastic mechanical properties of human cervical tissue using indentation

W Yao, K Yoshida, M Fernandez, J Vink… - Journal of the …, 2014 - Elsevier
The human cervix is an important mechanical barrier in pregnancy which must withstand the
compressive and tensile forces generated from the growing fetus. Premature cervical …

Analyzing three-dimensional ultrastructure of human cervical tissue using optical coherence tomography

Y Gan, W Yao, KM Myers, JY Vink… - Biomedical optics …, 2015 - opg.optica.org
During pregnancy, the uterine cervix is the mechanical barrier that prevents delivery of a
fetus. The underlying cervical collagen ultrastructure, which influences the overall …

Enhanced solute transport and steady mechanical stimulation in a novel dynamic perifusion bioreactor increase the efficiency of the in vitro culture of ovarian cortical …

G Fragomeni, L De Napoli, V De Gregorio… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction: We report the development and preliminary evaluation of a novel dynamic
bioreactor to culture ovarian cortical tissue strips that leverages tissue response to …