In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …

Gene regulatory networks have an important role in every process of life, including cell
differentiation, metabolism, the cell cycle and signal transduction. By understanding the …

A biofilm is an organized, resilient group of microbes in which individual cells acquire
properties, such as drug resistance, that are distinct from those observed in suspension …

Quantitative computational models play an increasingly important role in modern biology.
Such models typically involve many free parameters, and assigning their values is often a …

In many organisms, the circadian clock is composed of functionally coupled morning and
evening oscillators. In Arabidopsis, oscillator coupling relies on a core loop in which the …

Plant growth is driven by photosynthetic carbon fixation during the day. Some photosynthate
is accumulated, often as starch, to support nocturnal metabolism and growth at night. The …

Plants use day-length information to coordinate flowering time with the appropriate season
to maximize reproduction. In Arabidopsis, the long day–specific expression of CONSTANS …

Plants have evolved complex and sophisticated transcriptional networks that mediate
developmental changes in response to light. These light-regulated processes include …

The earth rotates on its axis every 24 h, with the result that any position on the earth's
surface alternately faces toward or away from the sun—day and night. That the metabolism …

A key step in the analysis of circadian data is to make an accurate estimate of the underlying
period. There are many different techniques and algorithms for determining period, all with …