Heart failure (HF) is a heterogeneous clinical syndrome marked by substantial morbidity and
mortality. The natural history of HF is well established; however, epidemiological data are …

Objective To investigate the dose–response association between pre‐and post‐diagnosis
body mass index (BMI) and heart failure (HF) mortality. Methods Eligible observational …

This study characterized the impact of post-weaning high-fat diet (HFD) and/or permethrin
(PER) treatment on heart dysfunction and fibrosis, as well as atherogenic risk, in rats by …

Exercise regimens may have differing effects in the presence of obesity. In addition to being
fat derived, adiponectin has recently been described as a myokine that regulates insulin …

Background With improving survival of patients with single ventricle physiology who
underwent Fontan palliation, there is also an increase in the prevalence of overweight and …

Background Left ventricular hypertrophy (LVH) is a marker of increased risk in developing
future life-threatening cardiovascular disease (CVD), however, it is unclear how CVD risk …

The incidence of obesity and diabetes is increasing rapidly worldwide. Obesity and
metabolic syndrome are strictly linked and represent the basis of different cardiovascular risk …

Background Sepsis and pulmonary arterial hypertension (PAH) may both present in a single
patient in the intensive care unit. The impact of PAH on the sepsis process is not well …

Background:​​​​​​ Heart failure (HF) remains one of the leading causes of death in the
United States. While many large-scale studies show a positive relationship between …

Heart failure (HF) with preserved ejection fraction (HFpEF) is a major public health problem
with cases projected to double over the next two decades. There are currently no US Food …