[图书][B] Pharmacological actions of cannabinoids
RG Pertwee - 2005 - Springer
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The endothelium, Part I: Multiple functions of the endothelial cells--focus on endothelium-derived vasoactive mediators
M Félétou - 2011 - books.google.com
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …
Inhibitors of connexin and pannexin channels as potential therapeutics
J Willebrords, M Maes, SC Yanguas… - Pharmacology & …, 2017 - Elsevier
While gap junctions support the exchange of a number of molecules between neighboring
cells, connexin hemichannels provide communication between the cytosol and the …
cells, connexin hemichannels provide communication between the cytosol and the …
Endocannabinoids mediate presynaptic inhibition of glutamatergic transmission in rat ventral tegmental area dopamine neurons through activation of CB1 receptors
The endogenous cannabinoid system has been shown to play a crucial role in controlling
neuronal excitability and synaptic transmission. In this study we investigated the effects of a …
neuronal excitability and synaptic transmission. In this study we investigated the effects of a …
The gap junction cellular internet: connexin hemichannels enter the signalling limelight
WH Evans, E De Vuyst, L Leybaert - Biochemical Journal, 2006 - portlandpress.com
Cxs (connexins), the protein subunits forming gap junction intercellular communication
channels, are transported to the plasma membrane after oligomerizing into hexameric …
channels, are transported to the plasma membrane after oligomerizing into hexameric …
Inverse agonism and neutral antagonism at cannabinoid CB1 receptors
RG Pertwee - Life sciences, 2005 - Elsevier
There are at least two types of cannabinoid receptor, CB1 and CB2, both G protein coupled.
CB1 receptors are expressed predominantly at nerve terminals and mediate inhibition of …
CB1 receptors are expressed predominantly at nerve terminals and mediate inhibition of …
Evidence for novel cannabinoid receptors
Cannabinoids, including the bioactive constituents of the marijuana plant, their synthetic
analogs, and endogenous lipids with cannabinoid-like activity, produce their biological …
analogs, and endogenous lipids with cannabinoid-like activity, produce their biological …
Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance
T Sugiura, Y Kobayashi, S Oka, K Waku - Prostaglandins, Leukotrienes and …, 2002 - Elsevier
N-arachidonoylethanolamine (anandamide) was the first endogenous cannabinoid receptor
ligand to be discovered. Dual synthetic pathways for anandamide have been proposed. One …
ligand to be discovered. Dual synthetic pathways for anandamide have been proposed. One …
The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism
The endogenous ligand of CB 1 cannabinoid receptors, anandamide, is also a full agonist at
vanilloid VR1 receptors for capsaicin and resiniferatoxin, thereby causing an increase in …
vanilloid VR1 receptors for capsaicin and resiniferatoxin, thereby causing an increase in …
Cellular signal transduction by anandamide and 2-arachidonoylglycerol
AC Howlett, S Mukhopadhyay - Chemistry and physics of lipids, 2000 - Elsevier
Anandamide (arachidonylethanolamide) and 2-arachidonoylglycerol mediate many of their
actions via either CB1 or CB2 cannabinoid receptor subtypes. These agonist-receptor …
actions via either CB1 or CB2 cannabinoid receptor subtypes. These agonist-receptor …