Adrenomedullin mitigates doxorubicin-induced nephrotoxicity in rats: role of oxidative stress, inflammation, apoptosis, and pyroptosis
Doxorubicin (DOX) is an anticancer antibiotic which has various effects in human cancers. It
is one of the commonly known causes of drug-induced nephrotoxicity, which results in acute …
is one of the commonly known causes of drug-induced nephrotoxicity, which results in acute …
Bioinformatics‐based identification of hepatocellular carcinoma‐associated hub genes and assessment of the restorative effect of tannic acid in rat liver exposed to …
H Tosun, H Karadas, H Ceylan - Cancer Medicine, 2024 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) is the most common type of primary liver
cancer, occurring mostly in individuals with chronic liver disease, but biomarkers for …
cancer, occurring mostly in individuals with chronic liver disease, but biomarkers for …
Tannic acid may ameliorate doxorubicin-induced changes in oxidative stress parameters in rat spleen
Doxorubicin (DOX) is a potent and broad-spectrum drug widely used in the treatment of
cancer. However, the toxicity and side effects of DOX on various organs limit its clinical use …
cancer. However, the toxicity and side effects of DOX on various organs limit its clinical use …
Neuroprotective potential of tannic acid against neurotoxic outputs of monosodium glutamate in rat cerebral cortex
MS Karagac, H Ceylan - Neurotoxicity Research, 2023 - Springer
Glutamate in monosodium glutamate (MSG), which is widely used in the food industry, has
an important role in major brain functions such as memory, learning, synapse formation, and …
an important role in major brain functions such as memory, learning, synapse formation, and …
Parthenolide as a potential analgesic in the treatment of paclitaxel-induced neuropathic pain: the rat modeling
In this study, we determined the therapeutic effect of parthenolide (PTL), the active
component of Tanacetum parthenium, on neuropathic pain caused by paclitaxel (PTX), a …
component of Tanacetum parthenium, on neuropathic pain caused by paclitaxel (PTX), a …
[HTML][HTML] Fibroblast-derived extracellular vesicles as trackable efficient transporters of an experimental nanodrug with fibrotic heart and lung targeting
J RuizdelRio, G Guedes, D Novillo, E Lecue… - Theranostics, 2024 - ncbi.nlm.nih.gov
The discovery of extracellular vesicles (EVs) as efficient exogenous biotransporters of
therapeutic agents into cells across biological membranes is an exciting emerging field …
therapeutic agents into cells across biological membranes is an exciting emerging field …
The hepatoprotective potential of tannic acid against doxorubicin‐induced hepatotoxicity: Insights into its antioxidative, anti‐inflammatory, and antiapoptotic …
Doxorubicin (DOX), which is frequently used in cancer treatment, has limited clinical use due
to adverse effects on healthy tissues, especially the liver. Therefore, it is necessary to …
to adverse effects on healthy tissues, especially the liver. Therefore, it is necessary to …
Effect of tannic acid on doxorubicin‐induced cellular stress: Expression levels of heat shock genes in rat spleen
Doxorubicin (DOX), an anthracycline group antibiotic, has been extensively employed as a
potent chemotherapeutic agent for treating solid and hematopoietic tumors in humans. Amid …
potent chemotherapeutic agent for treating solid and hematopoietic tumors in humans. Amid …
The interplay between doxorubicin chemotherapy, antioxidant system, and cardiotoxicity: Unrevealing of the protective potential of tannic acid
G Kansu, N Ozturk, MS Karagac… - Biotechnology and …, 2024 - Wiley Online Library
Cardiotoxicity is the leading side effect of anthracycline‐based chemotherapy. Therefore, it
has gained importance to reveal chemotherapy‐supporting strategies and reliable agents …
has gained importance to reveal chemotherapy‐supporting strategies and reliable agents …
Identification and verification of promising diagnostic genes in bisphenol A-associated breast cancer development via in silico analysis
M Akkus, H Ceylan - Frontiers in Life Sciences and Related …, 2023 - dergipark.org.tr
Lifestyle patterns and exposure to toxic chemicals or environmental pollutants are the
strongest risk factors for the chances of developing breast cancer, the leading and most …
strongest risk factors for the chances of developing breast cancer, the leading and most …