The prevalence of obesity has steadily increased over the past three decades both in the
United States and worldwide. Recent studies have shown the role of dietary polyphenols in …

The epidemic of obesity is a major challenge for health policymakers due to its far-reaching
effects on population health and potentially overwhelming financial burden on healthcare …

Metabolic syndrome (MS) is the term for a combination of hypertension, dyslipidemia, insulin
resistance, and central obesity as factors leading to cardiovascular and metabolic disease …

The physiological functions and bioavailability of flavonoids have been widely investigated
since their bioactivities were identified about 80 years ago. Quercetin is a typical flavonoid …

Rodents are widely used to mimic human diseases to improve understanding of the causes
and progression of disease symptoms and to test potential therapeutic interventions …

Reactive oxygen species, when released under controlled conditions and limited amounts,
contribute to cellular proliferation, senescence, and survival by acting as signaling …

Nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease, is a
multifactorial disease resulting from the interaction between environment, genetic …

The contemporary pathophysiological model of non-alcoholic fatty liver disease (NAFLD)
comprises multiple parallel pathways with a dynamic cross talk that cumulate in steatosis …

抄録 Gut microbiota have profound effects on bile acid metabolism by promoting
deconjugation, dehydrogenation, and dehydroxylation of primary bile acids in the distal …

Nonalcoholic fatty liver disease (NAFLD) represents a global healthcare burden since it is
epidemiologically related to obesity, type 2 diabetes (T2D) and Metabolic Syndrome (MetS) …