Hippo pathway is a master regulator of development, cell proliferation, stem cell function,
tissue regeneration, homeostasis, and organ size control. Hippo pathway relays signals from …

Studies of the processes leading to the construction of a bud and its separation from the
mother cell in Saccharomyces cerevisiae have provided foundational paradigms for the …

Candida auris has become a serious threat to public health. The mechanisms of how this
fungal pathogen adapts to the mammalian host are poorly understood. Here we report the …

Candida albicans exists as a commensal of mucosal surfaces and the gastrointestinal tract
without causing pathology. However, this fungus is also a common cause of mucosal and …

Simple Summary Cancer is increasingly viewed as a cell cycle disease in that the
dysregulation of the cell cycle machinery is a common feature in cancer. The Hippo …

The septation initiation network (SIN) regulates aspects of cell growth and division in
Schizosaccharomyces pombe and is essential for cytokinesis. Insufficient signalling results …

Studies on budding yeast have exposed the highly conserved mechanisms by which
duplicated chromosomes are evenly distributed to daughter cells at the metaphase …

The target of rapamycin (TOR) signalling pathway plays a key role in the coordination
between cellular growth and the cell cycle machinery in eukaryotes. The underlying …

Temporal control over protein phosphorylation and dephosphorylation is crucial for accurate
chromosome segregation and for completion of the cell division cycle during exit from …

The role of Cdc42 and its regulation during cytokinesis is not well understood. Using
biochemical and imaging approaches in budding yeast, we demonstrate that Cdc42 …