Venous malformations (VMs) are the most common vascular developmental anomalies
(birth defects). These defects are caused by developmental arrest of the venous system …

Specific staining of the extracellular matrix components is especially helpful in studying
tissue remodeling, particularly in the case of connective tissue pathologies. As developed by …

Background The role of the extracranial venous system in the pathology of central nervous
system (CNS) disorders and aging is largely unknown. It is acknowledged that the …

The extracellular matrix (ECM) confers transparency to the cornea because of the precise
organization of collagen fibrils and a wide variety of proteoglycans. We monitored the …

Abstract Structure-function relationships in tendons are directly influenced by the
arrangement of collagen fibres. However, the details of such arrangements in functionally …

Multiple sclerosis (MS) is a chronic, neurodegenerative disease of central nervous system,
characterized by inflammation, demyelination, and gliosis. It is commonly known the rapid …

Abstract Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disorder with
multisystemic features, including heart enlargement, heart valve dysfunction, and aortic …

UVB irradiation induces pro-inflammatory cytokines including interleukin-1 (IL-1) and tumor
necrosis factor-α (TNFα) in the skin. TNFα stimulates the chemotaxis of inflammatory cells to …

In the current study, we conducted a quantitative in-depth proteome and deglycoproteome
analysis of cerebrospinal fluid (CSF) from relapsing-remitting multiple sclerosis (RRMS) and …

The cross-sectional area of the superior sagittal sinus (SSS) is larger in multiple sclerosis
than normal and correlates with disease severity and progression. The sinus could be …