Plasminogen activator inhibitor antagonists

EL Madison, TK Brunck, JE Semple… - US Patent …, 2004 - Google Patents
Continuation-in-part of application No. 09/580,535, filed on May 26, 2000, and a
continuation-in-part of application No. 09/444,172, filed on Nov. 19, 1999, which is a …

Plasma kallikrein binding proteins

DJ Sexton, M Viswanathan - US Patent 8,816,055, 2014 - Google Patents
QXZGBUJJYSLZLT-UHFFFAOYSA-N H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH Natural
products NC (N)= NCCCC (N) C (= O) N1CCCC1C (= O) N1C (C (= O) NCC (= O) NC (CC …

Conjugates activated by cell surface proteases and therapeutic uses thereof

E Madison, J Semple, G Vlasuk, S Kemp… - US Patent App. 10 …, 2004 - Google Patents
2002-09-23 Assigned to CORVAS INTERNATIONAL, INC. reassignment CORVAS
INTERNATIONAL, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Treatment of mucositis with kallikrein inhibitors

A Sternlicht - US Patent 8,637,454, 2014 - Google Patents
6,087,473 A 7/2000 Conklin et a1 ' 2004/0209243 A1 10/2004 Nixon et a1. 6,090,916 A
7/2000 Vlasuk et a1 ' 2005/0004021 A1 l/2005 Sprecher et a1. 6,103,499 A 55/2000 …

Plasma kallikrein binding proteins

DJ Sexton, M Viswanathan - US Patent 8,822,653, 2014 - Google Patents
Plasma kallikrein is a serine protease component of the contact system and a potential drug
target for different inflammatory, cardiovascular, infectious (sepsis) and oncology diseases …

Prevention and reduction of blood loss

RC Ladner, AC Ley, S Hirani, A Williams - US Patent 8,124,586, 2012 - Google Patents
Related US Application Data Primary Examiner—Chih-Min Kam (63) Continuation of
application No. 1 1/796,272, filed on (74) Attorney, Agent, or Firm—Lando & Anastasi, LLP …

Prevention and reduction of blood loss

RC Ladner, AC Ley - US Patent 7,851,442, 2010 - Google Patents
Related US Application Data Continuation of application No. 1 1/796,272, filed on Apr. 27,
2007, now abandoned, which is a continuation of application No. 1 1/322,960, filed on Dec …

Prevention and reduction of blood loss

RC Ladner, AC Ley - US Patent 7,811,991, 2010 - Google Patents
Methods are described for preventing or reducing ischemia and/or systemic inflammatory
response in a patient Such as perioperative blood loss and/or systemic inflammatory …

Kallikrein-inhibitor therapies

RC Ladner, AC Ley, S Hirani, A Williams - US Patent 8,034,775, 2011 - Google Patents
US8034775B2 - Kallikrein-inhibitor therapies - Google Patents US8034775B2 - Kallikrein-inhibitor
therapies - Google Patents Kallikrein-inhibitor therapies Download PDF Info Publication …

Kallikrein Inhibitors and Anti-Thrombolytic Agents and Uses Thereof

H Blair, T Beck, RC Ladner - US Patent App. 11/931,496, 2008 - Google Patents
Methods, kits and compositions are described that include a non-naturally occurring
kallikrein inhibitor and an anti-thrombolytic agent, eg, an anti-fibrinolytic agent, for …