Review of ultrasound image guidance in external beam radiotherapy part II: intra-fraction motion management and novel applications
T O'Shea, J Bamber, D Fontanarosa… - Physics in medicine …, 2016 - iopscience.iop.org
Imaging has become an essential tool in modern radiotherapy (RT), being used to plan dose
delivery prior to treatment and verify target position before and during treatment. Ultrasound …
delivery prior to treatment and verify target position before and during treatment. Ultrasound …
Emerging applications of ultrasound-contrast agents in radiation therapy
Radiation therapy (RT) causes DNA damage through ionization, leading to double-strand
breaks. In addition, it generates reactive oxygen species (ROS), which are toxic to tumor …
breaks. In addition, it generates reactive oxygen species (ROS), which are toxic to tumor …
Non-invasive evaluation of breast cancer response to chemotherapy using quantitative ultrasonic backscatter parameters
Tumor response to neoadjuvant chemotherapy in patients (n= 30) with locally advanced
breast cancer (LABC) was examined using quantitative ultrasound. Three ultrasound …
breast cancer (LABC) was examined using quantitative ultrasound. Three ultrasound …
[HTML][HTML] Intravital imaging and cavitation monitoring of antivascular ultrasound in tumor microvasculature
Rationale: Focused ultrasound-stimulated microbubbles have been shown to be capable of
inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed …
inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed …
A study combining microbubble-mediated focused ultrasound and radiation therapy in the healthy rat brain and a F98 glioma model
SMP Fletcher, A Chisholm, M Lavelle, R Guthier… - Scientific Reports, 2024 - nature.com
Focused Ultrasound (FUS) has been shown to sensitize tumors outside the brain to
Radiotherapy (RT) through increased ceramide-mediated apoptosis. This study investigated …
Radiotherapy (RT) through increased ceramide-mediated apoptosis. This study investigated …
Synchronous Intravital Imaging and Cavitation Monitoring of Antivascular Focused Ultrasound in Tumor Microvasculature Using Monodisperse Low Boiling Point …
Focused ultrasound-stimulated microbubbles can induce blood flow shutdown and ischemic
necrosis at higher pressures in an approach termed antivascular ultrasound. Combined with …
necrosis at higher pressures in an approach termed antivascular ultrasound. Combined with …
Quantitative ultrasound characterization of locally advanced breast cancer by estimation of its scatterer properties
Purpose: Tumor grading is an important part of breast cancer diagnosis and currently
requires biopsy as its standard. Here, the authors investigate quantitative ultrasound …
requires biopsy as its standard. Here, the authors investigate quantitative ultrasound …
[HTML][HTML] Breast tumor response to ultrasound mediated excitation of microbubbles and radiation therapy in vivo
P Lai, C Tarapacki, WT Tran, A El Kaffas, J Lee… - …, 2016 - ncbi.nlm.nih.gov
Acoustically stimulated microbubbles have been demonstrated to perturb endothelial cells of
the vasculature resulting in biological effects. In the present study, vascular and tumor …
the vasculature resulting in biological effects. In the present study, vascular and tumor …
Implementation of non-invasive quantitative ultrasound in clinical cancer imaging
D Sharma, LO Osapoetra, GJ Czarnota - Cancers, 2022 - mdpi.com
Simple Summary At present, quantitative ultrasound (QUS) is increasingly utilized in cancer
imaging. Compared to other imaging modalities that take several days to weeks to assess …
imaging. Compared to other imaging modalities that take several days to weeks to assess …
Evaluating the effects of radiation and acoustically-stimulated microbubble therapy in an in vivo breast cancer model
D Sharma, CM Tarapacki, H Kandavel… - Plos one, 2023 - journals.plos.org
Ultrasound-stimulated microbubbles (USMB) cause localized vascular effects and sensitize
tumors to radiation therapy (XRT). We investigated acoustic parameter optimization for …
tumors to radiation therapy (XRT). We investigated acoustic parameter optimization for …