Health economic evaluations are comparative analyses of alternative courses of action in
terms of their costs and consequences. The Consolidated Health Economic Evaluation …

Background Billions of dollars are lost annually in health research that fails to create
meaningful benefits for patients. Engaging in research co-design–the meaningful …

Health economic evaluations are comparative analyses of alternative courses of action in
terms of their costs and consequences. The Consolidated Health Economic Evaluation …

Background The Medical Research Council published the second edition of its framework in
2006 on developing and evaluating complex interventions. Since then, there have been …

Background Numerous frameworks for supporting, evaluating and reporting patient and
public involvement in research exist. The literature is diverse and theoretically …

Background The certainty that prehabilitation improves postoperative outcomes is not clear.
The objective of this umbrella review (ie systematic review of systematic reviews) was to …

Global concern about problematic usage of the internet (PUI), and its public health and
societal costs, continues to grow, sharpened in focus under the privations of the COVID-19 …

Background In biomedical research, it is often desirable to seek consensus among
individuals who have differing perspectives and experience. This is important when …

Background Loss of arm function is a common problem after stroke. Robot-assisted training
might improve arm function and activities of daily living. We compared the clinical …

Importance Patient-reported outcome (PRO) data from clinical trials can provide valuable
evidence to inform shared decision making, labeling claims, clinical guidelines, and health …