Peripheral nerve regeneration with 3D printed bionic scaffolds loading neural crest stem cell derived Schwann cell progenitors

Y Li, S Lv, H Yuan, G Ye, W Mu, Y Fu… - Advanced Functional …, 2021 - Wiley Online Library
Peripheral nerve injuries are one of the most common types of traumatic damage to the
nervous system. Treatment of peripheral nerve injuries aims to promote axon regrowth by …

[HTML][HTML] Nerve repair using decellularized nerve grafts in rat models. A review of the literature

AB Lovati, D D'Arrigo, S Odella, P Tos… - Frontiers in cellular …, 2018 - frontiersin.org
Peripheral nerve regeneration after severe traumatic nerve injury is a relevant clinical
problem. Several different strategies have been investigated to solve the problem of bridging …

[HTML][HTML] Schwann cell-encapsulated chitosan-collagen hydrogel nerve conduit promotes peripheral nerve regeneration in rodent sciatic nerve defect models

H Takeya, S Itai, H Kimura, Y Kurashina, T Amemiya… - Scientific reports, 2023 - nature.com
Chitosan has various tissue regeneration effects. This study was designed to investigate the
nerve regeneration effect of Schwann cell (SC)-encapsulated chitosan-collagen hydrogel …

A compound scaffold with uniform longitudinally oriented guidance cues and a porous sheath promotes peripheral nerve regeneration in vivo

L Huang, L Zhu, X Shi, B Xia, Z Liu, S Zhu, Y Yang… - Acta biomaterialia, 2018 - Elsevier
Scaffolds with inner fillers that convey directional guidance cues represent promising
candidates for nerve repair. However, incorrect positioning or non-uniform distribution of …

[HTML][HTML] Electrohydrodynamic jet 3D printed nerve guide conduits (NGCs) for peripheral nerve injury repair

S Vijayavenkataraman, S Zhang, S Thaharah, G Sriram… - Polymers, 2018 - mdpi.com
The prevalence of peripheral nerve injuries resulting in loss of motor function, sensory
function, or both, is on the rise. Artificial Nerve Guide Conduits (NGCs) are considered an …

Promoting nerve regeneration: electrical stimulation, gene therapy, and beyond

AL O'Brien, JM West, TM Saffari, M Nguyen… - …, 2022 - journals.physiology.org
Peripheral nerve injuries often result in life-altering functional deficits even with optimal
management. Unlike the central nervous system, peripheral nerves have the ability to …

[HTML][HTML] Peripheral nerve regeneration with conduits: use of vein tubes

RG Sabongi, M Fernandes… - Neural regeneration …, 2015 - journals.lww.com
Abstract Treatment of peripheral nerve injuries remains a challenge to modern medicine due
to the complexity of the neurobiological nerve regenerating process. There is a greater …

[HTML][HTML] Nerve autografts and tissue-engineered materials for the repair of peripheral nerve injuries: a 5-year bibliometric analysis

Y Gao, Y Wang, D Kong, B Qu, X Su… - Neural regeneration …, 2015 - journals.lww.com
With advances in biomedical methods, tissue-engineered materials have developed rapidly
as an alternative to nerve autografts for the repair of peripheral nerve injuries. However, the …

Local FK506 drug delivery enhances nerve regeneration through fresh, unprocessed peripheral nerve allografts

KJ Zuo, G Shafa, K Chan, J Zhang, C Hawkins… - Experimental …, 2021 - Elsevier
Objective Nerve allografts offer many advantages in the reconstruction of peripheral nerve
gaps: they retain their native microstructure, contain pro-regenerative Schwann cells, are …

[HTML][HTML] Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration

H Kimura, T Ouchi, S Shibata, T Amemiya, N Nagoshi… - Scientific reports, 2018 - nature.com
Strategies for therapeutic cell transplantation have been assessed for use in the treatment of
massive peripheral nerve defects. To support safe and efficient cell transplantation, we have …