Prognostic and predictive value of liquid biopsy-derived androgen receptor variant 7 (AR-V7) in prostate cancer: a systematic review and meta-analysis

T Khan, TM Becker, KF Scott, J Descallar… - Frontiers in …, 2022 - frontiersin.org
In advanced prostate cancer, access to recent diagnostic tissue samples is restricted and
this affects the analysis of the association of evolving biomarkers such as AR-V7 with …

The prognostic value of androgen receptor splice variant 7 in castration-resistant prostate cancer treated with novel hormonal therapy or chemotherapy: a systematic …

Z Wang, H Shen, N Ma, Q Li, Y Mao, C Wang… - Frontiers in …, 2020 - frontiersin.org
Purpose This study aimed to evaluate the prognostic role of AR-V7 in terms of prostate-
specific antigen (PSA) response, progression-free survival (PFS), and overall survival (OS) …

177Lu-PSMA-617 and idronoxil in men with end-stage metastatic castration-resistant prostate cancer (LuPIN): patient outcomes and predictors of treatment response …

S Pathmanandavel, M Crumbaker… - Journal of Nuclear …, 2022 - Soc Nuclear Med
177Lu-PSMA-617 is an effective therapy for metastatic castration-resistant prostate cancer
(mCRPC). However, treatment resistance occurs frequently, and combination therapies may …

Impact of Asian race on prognosis in de novo metastatic prostate cancer

X Ni, M Luu, W Ma, T Zhang, Y Wei… - Journal of the National …, 2023 - jnccn.org
Background: Little is known about the impact of Asian race on the long-term survival
outcomes of males with de novo metastatic prostate cancer (PCa). Understanding racial …

An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq

A Kolliari-Turner, G Lima, G Wang, FR Malinsky… - BMC medical …, 2023 - Springer
Abstract Background The effects of Anabolic Androgenic Steroids (AAS) are largely
illustrated through Androgen Receptor induced gene transcription, yet RNA-Seq has yet to …

Liquid biopsy‐based targeted gene screening highlights tumor cell subtypes in patients with advanced prostate cancer

S Derderian, Q Vesval, MD Wissing… - Clinical and …, 2022 - Wiley Online Library
Prostate cancer (PCa) clinical heterogeneity underscores tumor heterogeneity, which may
be best defined by cell subtypes. To test if cell subtypes contributing to progression can be …

Independent prognostic impact of plasma NCOA2 alterations in metastatic castration‐resistant prostate cancer

H Fettke, EM Kwan, P Bukczynska, JA Steen… - The …, 2021 - Wiley Online Library
Background The androgen receptor (AR) pathway‐associated gene nuclear receptor
coactivator 2 (NCOA2) has an established oncogenic role in early prostate cancer and …

Upregulation of potential regulatory signaling molecules correlate with androgen receptor splice variants AR-V7 and AR-V567es in prostate cancer metastasis

I Kiliccioglu, CY Bilen, S Sozen, E Konac - Gene, 2021 - Elsevier
Aim Androgen receptor splice variants (AR-Vs) produced by alternative splicing of the AR
play an important role in the treatment resistance and progression of prostate cancer (PCa) …

Systematic review and integrated analysis of prognostic gene signatures for prostate cancer patients

Y An, W Lu, S Li, X Lu, Y Zhang, D Han, D Su, J Jia… - Discover Oncology, 2023 - Springer
Prostate cancer (PC) is one of the most common cancers in men and becoming the second
leading cause of cancer fatalities. At present, the lack of effective strategies for prognosis of …

The MMAAS Project: an observational human study investigating the effect of anabolic androgenic steroid use on gene expression and the molecular mechanism of …

G Lima, A Kolliari-Turner, G Wang, P Ho… - Clinical Journal of …, 2023 - journals.lww.com
Objective: It remains unknown whether myonuclei remain elevated post anabolic-
androgenic steroid (AAS) usage in humans. Limited data exist on AAS-induced changes in …