Tremendous strides have been made in our understanding of the neurobiological substrates
of memory–the so-called memory “engram”. Here, we integrate recent progress in the …

Conscious experiences involve subjective qualities, such as colours, sounds, smells and
emotions. In this Perspective, we argue that these subjective qualities can be understood in …

The hippocampus and its extended network contribute to encoding and recall of episodic
experiences. Drawing from recent anatomical, physiological, and behavioral studies, we …

Memories are believed to be encoded by sparse ensembles of neurons in the brain.
However, it remains unclear whether there is functional heterogeneity within individual …

In Consciousness We Trust is a synthesis of Hakwan Lau's 20-year research programme
exploring the neuroscience of consciousness. Discussing studies from his own laboratory …

Mice display signs of fear when neurons that express cFos during fear conditioning are
artificially reactivated. This finding gave rise to the notion that cFos marks neurons that …

We review the literature on systems consolidation by providing a brief history of the field to
place the current research in proper perspective. We cover the literature on both humans …

Memories are stored in the brain as cellular ensembles activated during learning and
reactivated during retrieval. Using the Tet-tag system in mice, we label dorsal dentate gyrus …

For decades, the mammalian hippocampus has been the focus of cellular, anatomical,
behavioral, and computational studies aimed at understanding the fundamental …

Highlights•Endogenous fluctuations in cellular excitability support time-stamping and
memory-updating across time and experience.•Molecularly distinct subensembles may …