Skin is the largest organ of the human body, having the purpose of regulating temperature,
protecting us from microbes or mechanical shocks, and allowing the sensations from touch …

The protection and interrogation of pancreatic β-cell health and function ex vivo is a
fundamental aspect of diabetes research, including mechanistic studies, evaluation of β-cell …

Aging induces marked alterations in the structural, mechanical, and transport properties in
the extracellular matrix (ECM). To provide computational data on the impact of aging-related …

Computational modeling of drug delivery is becoming an indispensable tool for advancing
drug development pipeline, particularly in nanomedicine where a rational design strategy is …

Penetration of nanoscale therapeutic agents into the extracellular matrix (ECM) of a tumor is
a limiting factor for the sufficient delivery of drugs in tumors. Ultrasound (US) in combination …

We present a high-throughput microfluidics technique facilitating in situ measurements of
cell mechanics parameters at the dorsal side of the cell, including molecular binding …

The present study aims to characterize and understand the dropwise gelation-dehydration
phenomena during drop-on-demand (DOD) printing of hydrogel-based soft materials …

A biocompatible bone graft for implanting into a bone wound site or screening a bone
disease drug, comprising a porous scaffold structure made from a tannin-hydroxyapatite …

Background and objective Interstitial flow (IF) is a creeping flow through the interstitial space
of the extracellular matrix (ECM). IF plays a key role in diverse biological functions, such as …

Skeletal defects resulting from trauma and disease represent a major clinical problem
worldwide exacerbated further by global population growth and an increasing number of …