[HTML][HTML] Cytotoxic CD4 T cells—friend or foe during viral infection?
JA Juno, D Van Bockel, SJ Kent, AD Kelleher… - Frontiers in …, 2017 - frontiersin.org
CD4 T cells with cytotoxic function were once thought to be an artifact due to long-term in
vitro cultures but have in more recent years become accepted and reported in the literature …
vitro cultures but have in more recent years become accepted and reported in the literature …
Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn
NM Martinez, KW Lynch - Immunological reviews, 2013 - Wiley Online Library
Most mammalian pre‐mRNA s are alternatively spliced in a manner that alters the resulting
open reading frame. Consequently, alternative pre‐mRNA splicing provides an important …
open reading frame. Consequently, alternative pre‐mRNA splicing provides an important …
[HTML][HTML] Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
NR West, K Milne, PT Truong, N Macpherson… - Breast cancer …, 2011 - Springer
Introduction Infiltration of breast tumors by tumor-infiltrating lymphocytes (TIL) has been
associated with sensitivity to anthracycline-based chemotherapy. However, it is unclear …
associated with sensitivity to anthracycline-based chemotherapy. However, it is unclear …
High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
Microsatellite instability (MSI) characterizes colorectal carcinomas (CRCs) in hereditary
nonpolyposis colorectal cancer (HNPCC) syndrome and a proportion of sporadic CRCs …
nonpolyposis colorectal cancer (HNPCC) syndrome and a proportion of sporadic CRCs …
Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency
F Altare, A Durandy, D Lammas, JF Emile… - Science, 1998 - science.org
In humans, interferon γ (IFN-γ) receptor deficiency leads to a predisposition to mycobacterial
infections and impairs the formation of mature granulomas. Interleukin-12 (IL-12) receptor …
infections and impairs the formation of mature granulomas. Interleukin-12 (IL-12) receptor …
Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells
Abstract Purpose: Recent studies of Hodgkin's lymphoma (HL) have suggested that the
presence of regulatory T cells in the reactive background may explain the inhibition of the …
presence of regulatory T cells in the reactive background may explain the inhibition of the …
Mycobacterium tuberculosis Growth at theCavity Surface: a Microenvironment with FailedImmunity
G Kaplan, FA Post, AL Moreira, H Wainwright… - Infection and …, 2003 - Am Soc Microbiol
Protective immunity against pulmonary tuberculosis (TB) is characterized by the formation in
the lungs of granulomas consisting of macrophages and activated T cells producing tumor …
the lungs of granulomas consisting of macrophages and activated T cells producing tumor …
Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone
J Pudney, AJ Quayle, DJ Anderson - Biology of reproduction, 2005 - academic.oup.com
Cell-mediated immunity (CMI) is key to defense against intracellular pathogens such as
Chlamydia trachomatis and viruses that infect the lower female genital tract, but little is …
Chlamydia trachomatis and viruses that infect the lower female genital tract, but little is …
Primary cutaneous CD8-positive epidermotropic cytotoxic T cell lymphomas: a distinct clinicopathological entity with an aggressive clinical behavior
Cutaneous T cell lymphomas (CTCL) generally have the phenotype of CD3+, CD4+,
CD45RO+ memory T cells. CTCL expressing a CD8+ T cell phenotype are extremely rare …
CD45RO+ memory T cells. CTCL expressing a CD8+ T cell phenotype are extremely rare …
A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells
Q Tian, M Streuli, H Saito, SF Schlossman, P Anderson - Cell, 1991 - cell.com
Cytolytic lymphocytes (CTLs) are characterized by their inclusion of cytoplasmic granules
containing effector molecules such as perforin and the serine proteases. Here we describe …
containing effector molecules such as perforin and the serine proteases. Here we describe …