Exercise intolerance in heart failure: central role for the pulmonary system

S Lalande, TJ Cross, ML Keller-Ross… - Exercise and sport …, 2020 - journals.lww.com
Chronic heart failure (HF) is a complex multiorgan syndrome characterized by
pathophysiological changes in cardiac, vascular, musculoskeletal, endocrine, and …

The interactions between respiratory and cardiovascular systems in systolic heart failure

TJ Cross, CH Kim, BD Johnson… - Journal of Applied …, 2020 - journals.physiology.org
Heart failure (HF) is a complex and multifaceted disease. The disease affects multiple organ
systems, including the respiratory system. This review provides three unique examples …

The resistive and elastic work of breathing during exercise in patients with chronic heart failure

TJ Cross, S Sabapathy, KC Beck… - European …, 2012 - Eur Respiratory Soc
Patients with heart failure (HF) display numerous derangements in ventilatory function,
which together serve to increase the work of breathing (W b) during exercise. However, the …

Lung function abnormalities are highly frequent in patients with heart failure and preserved ejection fraction

R Andrea, A López-Giraldo, C Falces… - Heart, Lung and …, 2014 - Elsevier
Background Heart failure with preserved ejection fraction (HFPEF) is the most prevalent form
of heart failure in outpatients. Yet, the pathophysiology of this syndrome is unclear and …

Pulmonary limitations in heart failure

I Cundrle, LJ Olson… - Clinics in chest medicine, 2019 - chestmed.theclinics.com
The heart and lungs are intimately related anatomically and physiologically because they
share the enclosed thoracic cavity, are exposed to similar intrathoracic pressures, have a …

Lung capillary injury and repair in left heart disease: a new target for therapy?

S Azarbar, J Dupuis - Clinical science, 2014 - portlandpress.com
The lungs are the primary organs affected in LHD (left heart disease). Increased left atrial
pressure leads to pulmonary alveolar–capillary stress failure, resulting in cycles of alveolar …

射血分数保留的心力衰竭患者肺功能异常特征研究

陈浩然, 麦妙美, 李格丽, 欧阳瑞萍, 何洁华, 米荟颍… - 中国全科医学, 2020 - chinagp.net
背景射血分数保留的心力衰竭(HFpEF) 是门诊最常见的心力衰竭(心衰) 形式,
但该综合征的病理生理机制仍不清楚, 药物治疗不能改善预后. 因为气短是HFpEF …

The blood transfer conductance for nitric oxide: Infinite vs. finite θNO

KE Coffman, SC Chase, BJ Taylor… - Respiratory physiology & …, 2017 - Elsevier
Whether the specific blood transfer conductance for nitric oxide (NO) with hemoglobin (θ
NO) is finite or infinite is controversial but important in the calculation of alveolar capillary …

Effect of supine posture on airway blood flow and pulmonary function in stable heart failure

ML Ceridon, NR Morris, TP Olson, S Lalande… - Respiratory physiology …, 2011 - Elsevier
BACKGROUND: The aim of this study was to determine the relationship between body
position, pulmonary function (PF) and bronchial blood flow (Qaw) in a group of heart failure …

Pulmonary function assessment post‐left ventricular assist device implantation

P Sajgalik, CH Kim, JM Stulak, SS Kushwaha… - ESC Heart …, 2019 - Wiley Online Library
Aim The lungs—and particularly the alveolar‐capillary membrane—may be sensitive to
continuous flow (CF) and pulmonary pressure alterations in heart failure (HF). We aimed to …