Vascular dysfunction in preeclampsia
MA Opichka, MW Rappelt, DD Gutterman, JL Grobe… - Cells, 2021 - mdpi.com
Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …
IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies
A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …
mediating innate and adaptive immunity and multiple physiological processes, including …
The role of immune cells and mediators in preeclampsia
E Deer, O Herrock, N Campbell, D Cornelius… - Nature Reviews …, 2023 - nature.com
Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …
Monocytes and macrophages in pregnancy: The good, the bad, and the ugly
H True, M Blanton, S Sureshchandra… - Immunological …, 2022 - Wiley Online Library
A successful human pregnancy requires precisely timed adaptations by the maternal
immune system to support fetal growth while simultaneously protecting mother and fetus …
immune system to support fetal growth while simultaneously protecting mother and fetus …
Improving preeclampsia risk prediction by modeling pregnancy trajectories from routinely collected electronic medical record data
Preeclampsia is a heterogeneous and complex disease associated with rising morbidity and
mortality in pregnant women and newborns in the US. Early recognition of patients at risk is …
mortality in pregnant women and newborns in the US. Early recognition of patients at risk is …
Role of the monocyte–macrophage system in normal pregnancy and preeclampsia
The proper functioning of the monocyte–macrophage system, an important unit of innate
immunity, ensures the normal course of pregnancy. In this review, we present the current …
immunity, ensures the normal course of pregnancy. In this review, we present the current …
[HTML][HTML] Multimodal profiling of term human decidua demonstrates immune adaptations with pregravid obesity
S Sureshchandra, BM Doratt, H True, N Mendoza… - Cell reports, 2023 - cell.com
Leukocyte diversity of the first-trimester maternal-fetal interface has been extensively
described; however, the immunological landscape of the term decidua remains poorly …
described; however, the immunological landscape of the term decidua remains poorly …
Maternal microbiome in preeclampsia pathophysiology and implications on offspring health
JA Ishimwe - Physiological reports, 2021 - Wiley Online Library
Preeclampsia is a devastating hypertensive pregnancy disorder that currently affects 2%–
8% of pregnancies worldwide. It is associated with maternal and fetal mortality and morbidity …
8% of pregnancies worldwide. It is associated with maternal and fetal mortality and morbidity …
Placental galectins are key players in regulating the maternal adaptive immune response
Galectins are potent immunomodulators that regulate maternal immune responses in
pregnancy and prevent the rejection of the semi-allogeneic fetus that also occurs in …
pregnancy and prevent the rejection of the semi-allogeneic fetus that also occurs in …
Placental and maternal sFlt1/PlGF expression in gestational diabetes mellitus
AM Nuzzo, D Giuffrida, L Moretti, P Re, G Grassi… - Scientific Reports, 2021 - nature.com
Gestational diabetes mellitus (GDM) and preeclampsia (PE) are both characterized by
endothelial dysfunction and GDM women have higher incidence of PE. The placenta plays a …
endothelial dysfunction and GDM women have higher incidence of PE. The placenta plays a …