Pathophysiology from preconception, during pregnancy, and beyond

MF Hivert, H Backman, K Benhalima, P Catalano… - The Lancet, 2024 - thelancet.com
Gestational diabetes is the most common medical complication in pregnancy. Historically,
gestational diabetes was considered a pregnancy complication involving treatment of rising …

Placental endocrine activity: adaptation and disruption of maternal glucose metabolism in pregnancy and the influence of fetal sex

C Stern, S Schwarz, G Moser, S Cvitic… - International journal of …, 2021 - mdpi.com
The placenta is an endocrine fetal organ, which secretes a plethora of steroid-and proteo-
hormones, metabolic proteins, growth factors, and cytokines in order to adapt maternal …

A pathway level analysis of PFAS exposure and risk of gestational diabetes mellitus

RL Birru, HW Liang, F Farooq, M Bedi, M Feghali… - Environmental …, 2021 - Springer
Per-and polyfluoroalkyl substances (PFAS) have been found to be associated with
gestational diabetes mellitus (GDM) development, a maternal health disorder in pregnancy …

High folate, perturbed one-carbon metabolism and gestational diabetes mellitus

JM Williamson, AL Arthurs, MD Smith, CT Roberts… - Nutrients, 2022 - mdpi.com
Folate is a dietary micronutrient essential to one-carbon metabolism. The World Health
Organisation recommends folic acid (FA) supplementation pre-conception and in early …

Maternal metabolic factors and the association with gestational diabetes: a systematic review and meta‐analysis

N Habibi, A Mousa, CT Tay… - Diabetes/Metabolism …, 2022 - Wiley Online Library
Gestational diabetes (GDM) is associated with several adverse outcomes for the mother and
child. Higher levels of individual lipids are associated with risk of GDM and metabolic …

Gestational diabetes mellitus screening and diagnosis

UY Sert, AS Ozgu-Erdinc - Diabetes: from Research to Clinical Practice …, 2021 - Springer
An ideal screening test for gestational diabetes should be capable of identifying not only
women with the disease but also the women with a high risk of developing gestational …

First trimester neutrophil to lymphocyte ratio (NLR) and pregnancy outcome

V Christoforaki, Z Zafeiriou, G Daskalakis… - Journal of Obstetrics …, 2020 - Taylor & Francis
In early pregnancy, miscarriage is the most common complication. The early identification of
women at high risk for miscarriage could improve pregnancy outcomes. We investigated …

Placental growth factor and pregnancy-associated plasma protein-A as potential early predictors of gestational diabetes mellitus

V Yanachkova, R Staynova, T Stankova, Z Kamenov - Medicina, 2023 - mdpi.com
Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications
and one of the main causes of adverse pregnancy outcomes. An early diagnosis of GDM is …

Placental secretome characterization identifies candidates for pregnancy complications

T Napso, X Zhao, MI Lligoña, I Sandovici… - Communications …, 2021 - nature.com
Alterations in maternal physiological adaptation during pregnancy lead to complications,
including abnormal birthweight and gestational diabetes. Maternal adaptations are driven by …

[HTML][HTML] The vitamin D receptor (VDR) protects pancreatic beta cells against Forkhead box class O1 (FOXO1)-induced mitochondrial dysfunction and cell apoptosis

C Chen, Y Luo, Y Su, L Teng - Biomedicine & pharmacotherapy, 2019 - Elsevier
Vitamin D deficiency is identified as a risk factor for gestational diabetes mellitus (GDM).
Forkhead box class O1 (FoxO1) is closely related to GDM; however, the role of vitamin D …