Origin and heterogeneity of tissue myeloid cells: a focus on GMP-derived monocytes and neutrophils

LG Ng, Z Liu, I Kwok, F Ginhoux - Annual Review of …, 2023 - annualreviews.org
Myeloid cells are a significant proportion of leukocytes within tissues, comprising
granulocytes, monocytes, dendritic cells, and macrophages. With the identification of various …

The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis

N Ikeda, H Kubota, R Suzuki, M Morita, A Yoshimura… - Cell Reports, 2023 - cell.com
Inflammatory stimuli cause a state of emergency myelopoiesis leading to neutrophil-like
monocyte expansion. However, their function, the committed precursors, or growth factors …

Effective antibacterial agents in modern wound dressings: a review

S Torabi, SA Hassanzadeh-Tabrizi - Biofouling, 2024 - Taylor & Francis
Wound infections are a significant concern in healthcare, leading to long healing times.
Traditional approaches for managing wound infections rely heavily on systemic antibiotics …

Noncovalent co-assembly of aminoglycoside antibiotics@ tannic acid nanoparticles for off-the-shelf treatment of pulmonary and cutaneous infections

G Yang, C Wang, Y Wang, X Liu, Y Zhang, M Xu… - Chemical Engineering …, 2023 - Elsevier
Antibiotics still serve as the first choice for combating bacterial infections, whereas the
therapeutic efficiency of antibiotics needs to be further augmented. Here, we report the …

Aberrant monocytopoiesis drives granuloma development in sarcoidosis

R Hiranuma, R Sato, K Yamaguchi… - International …, 2024 - academic.oup.com
In sarcoidosis, granulomas develop in multiple organs including the liver and lungs.
Although mechanistic target of rapamycin complex 1 (mTORC1) activation in macrophages …

GCRV-II invades monocytes/macrophages and induces macrophage polarization and apoptosis in tissues to facilitate viral replication and dissemination

N Xia, Y Zhang, W Zhu, J Su - Journal of Virology, 2024 - Am Soc Microbiol
Grass carp reovirus (GCRV), particularly the highly prevalent type II GCRV (GCRV-II),
causes huge losses in the aquaculture industry. However, little is known about the …

Behind the monocyte's mystique: uncovering their developmental trajectories and fates

YC Teh, MY Chooi, SZ Chong - Discovery Immunology, 2023 - academic.oup.com
Monocytes are circulating myeloid cells that are derived from dedicated progenitors in the
bone marrow. Originally thought of as mere precursors for the replacement of tissue …

Plasma galectin-9 levels correlate with blood monocyte turnover and predict simian/human immunodeficiency virus disease progression

L Zablocki-Thomas, A Ardeshir, N Takahashi… - Translational Medicine …, 2024 - Springer
Background Late-stage human immunodeficiency virus (HIV) infection is typically
characterized by low CD4+ T-cell count. We previously showed that profound changes in the …

Novel monocyte sub-populations in Sprague Dawley rats revealed by detailed analysis of CD43 and CD11b expression using a single-stain 11-colour fluorescence …

ROH Doig, S Jenkner, R Grose, M Lewis, D Thomas… - 2024 - researchsquare.com
Monocytes are a diverse population of white blood cells with critical roles in immunity and
inflammation. The rat is commonly used for immunological investigations, but …

Exploring Immune-Related Gene Expression Up To The First 24-Hour For Predicting Sepsis Outcomes Based On Comprehensive Bioinformatics Analysis And …

H Deng, J Li, AA Shah, L Huang, L Ge, W Ouyang - 2023 - researchsquare.com
Background: Host immune dysregulation participates in the prognosis of sepsis with high
morbidity and mortality. Our study aimed to identify the roles of immuneassociated genes …