[HTML][HTML] Role of red blood cells in clinically relevant bleeding tendencies and complications
The multiple roles of red blood cells (RBCs) are often neglected as contributors in
hemostasis and thrombosis. Proactive opportunities to increase RBC numbers, either …
hemostasis and thrombosis. Proactive opportunities to increase RBC numbers, either …
[HTML][HTML] Fibrinolysis: an illustrated review
In response to vessel injury (or other pathological conditions), the hemostatic process is
activated, resulting in a fibrous, cellular-rich structure commonly referred to as a blood clot …
activated, resulting in a fibrous, cellular-rich structure commonly referred to as a blood clot …
Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage
Non-compressible hemorrhage is an unmet clinical challenge that accounts for high
mortality in trauma. Rapid pressurized blood flows under hemorrhage impair the function …
mortality in trauma. Rapid pressurized blood flows under hemorrhage impair the function …
Structural analysis of ischemic stroke thrombi: histological indications for therapy resistance
S Staessens, F Denorme, O Francois… - …, 2019 - pmc.ncbi.nlm.nih.gov
Ischemic stroke is caused by a thromboembolic occlusion of cerebral arteries. Treatment is
focused on fast and efficient removal of the occluding thrombus, either via intravenous …
focused on fast and efficient removal of the occluding thrombus, either via intravenous …
[HTML][HTML] Blood clot contraction: mechanisms, pathophysiology, and disease
RI Litvinov, JW Weisel - Research and Practice in Thrombosis and …, 2023 - Elsevier
A State of the Art lecture titled “Blood Clot Contraction: Mechanisms, Pathophysiology, and
Disease” was presented at the International Society on Thrombosis and Haemostasis (ISTH) …
Disease” was presented at the International Society on Thrombosis and Haemostasis (ISTH) …
Altered platelet and coagulation function in moderate-to-severe COVID-19
To reveal if coagulopathies relate to the course of COVID-19, we examined 255 patients with
moderate and severe COVID-19, receiving anticoagulants and immunosuppressive drugs …
moderate and severe COVID-19, receiving anticoagulants and immunosuppressive drugs …
Mechanical behavior of in vitro blood clots and the implications for acute ischemic stroke treatment
S Johnson, J Chueh, MJ Gounis, R McCarthy… - Journal of …, 2020 - jnis.bmj.com
Background Clot mechanical properties are influenced by composition and the arrangement
of components within the clot. This work investigates the effects of platelet-driven contraction …
of components within the clot. This work investigates the effects of platelet-driven contraction …
[HTML][HTML] Pathologically stiff erythrocytes impede contraction of blood clots
Background Blood clot contraction, volume shrinkage of the clot, is driven by platelet
contraction and accompanied by compaction of the erythrocytes and their gradual shape …
contraction and accompanied by compaction of the erythrocytes and their gradual shape …
A whole blood thrombus mimic: constitutive behavior under simple shear
GP Sugerman, S Kakaletsis, P Thakkar… - journal of the …, 2021 - Elsevier
Deep vein thrombosis and pulmonary embolism affect 300,000–600,000 patients each year
in the US. To better understand the highly mechanical pathophysiology of pulmonary …
in the US. To better understand the highly mechanical pathophysiology of pulmonary …
Immunothrombosis and vascular heterogeneity in cerebral cavernous malformation
MA Globisch, FC Onyeogaziri… - Blood, The Journal …, 2022 - ashpublications.org
Cerebral cavernous malformation (CCM) is a neurovascular disease that results in various
neurological symptoms. Thrombi have been reported in surgically resected CCM patient …
neurological symptoms. Thrombi have been reported in surgically resected CCM patient …